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Catalog Number:
47678
CAS Number:
39637-99-5
Chlorure de (R)-(-)-a-méthoxy-a-(trifluorométhyl)phénylacétyle (environ 18 % dans le dichlorométhane, environ 1,0 mol/L) [pour la détermination de la pureté optique des alcools et des amines]
Purity:
≥ 99 % (ee)
Synonym(s):
Chlorure d'acide (-)-Mosher (environ 18 % dans le dichlorométhane, environ 1,0 mol/L), (R)-(-)-MTPA-Cl
Hazmat
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$187.50 /1G
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Product Information

(R)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride is a valuable compound widely utilized in organic synthesis and pharmaceutical research. This compound, characterized by its trifluoromethyl and methoxy groups, offers unique reactivity that makes it an essential building block in the development of various chemical entities. Its high reactivity allows for efficient acylation reactions, making it particularly useful in the synthesis of complex molecules, including pharmaceuticals and agrochemicals. Researchers appreciate its ability to introduce trifluoromethyl groups, which can enhance the biological activity and metabolic stability of drug candidates.

In addition to its synthetic applications, (R)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride serves as a versatile reagent in the preparation of chiral intermediates. Its chirality is crucial for the development of enantiomerically pure compounds, which are increasingly important in the pharmaceutical industry. This compound's solubility in dichloromethane facilitates its use in various reaction conditions, making it a practical choice for chemists seeking efficiency and reliability in their synthetic pathways.

Synonyms
Chlorure d'acide (-)-Mosher (environ 18 % dans le dichlorométhane, environ 1,0 mol/L), (R)-(-)-MTPA-Cl
CAS Number
39637-99-5
Purity
≥ 99 % (ee)
Molecular Formula
C10H8ClF3O2
Molecular Weight
0
PubChem ID
604961
Density
1.353
Appearance
Liquide clair et incolore
Boiling Point
213 - 214 °C
Refractive Index
n20/D = 1,46
Conditions
Conserver entre 2 et 8 °C, sous gaz inerte.
Warnings
9
General Information
Synonyms
Chlorure d'acide (-)-Mosher (environ 18 % dans le dichlorométhane, environ 1,0 mol/L), (R)-(-)-MTPA-Cl
CAS Number
39637-99-5
Purity
≥ 99 % (ee)
Molecular Formula
C10H8ClF3O2
Molecular Weight
0
PubChem ID
604961
Density
1.353
Appearance
Liquide clair et incolore
Boiling Point
213 - 214 °C
Refractive Index
n20/D = 1,46
Conditions
Conserver entre 2 et 8 °C, sous gaz inerte.
Warnings
9
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
9
Applications

(R)-(-)-a-Methoxy-a-(trifluoromethyl)phenylacetyl chloride is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those requiring trifluoromethyl groups, enhancing their biological activity and stability.
  • Development of Agrochemicals: It plays a significant role in the formulation of agrochemicals, improving the efficacy of pesticides and herbicides by modifying their chemical properties for better performance in agricultural applications.
  • Material Science: The compound is used in the development of advanced materials, particularly in creating polymers with enhanced thermal and chemical resistance, which are crucial for various industrial applications.
  • Research in Medicinal Chemistry: It is a valuable reagent in medicinal chemistry for the exploration of new drug candidates, allowing researchers to modify existing compounds to improve their pharmacological profiles.
  • Analytical Chemistry: This chemical is employed in analytical methods for the detection and quantification of specific compounds, providing researchers with reliable data for their studies.

Citations