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Catalog Number:
31648
CAS Number:
64987-84-4
Ester NHS de l'acide 4-(maléimidométhyl)-benzoïque
Synonym(s):
2,5-dioxopyrrolidine-1-yl4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)méthyl)benzoate, 4-Mal-MBz-NHS
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$127.79 /100 mg
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Product Information

4-(Maleimidomethyl)-benzoic acid-NHS ester is a versatile compound widely utilized in bioconjugation and protein labeling applications. This NHS ester derivative is particularly valued for its ability to form stable amide bonds with primary amines, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its unique maleimide functionality allows for selective conjugation to thiol-containing biomolecules, facilitating the development of targeted drug delivery systems and diagnostic agents.

In addition to its applications in research, this compound is also beneficial in the production of antibody-drug conjugates (ADCs), which are pivotal in cancer therapy. By enabling precise attachment of therapeutic agents to antibodies, 4-(Maleimidomethyl)-benzoic acid-NHS ester enhances the efficacy and specificity of treatments, minimizing off-target effects. Its ease of use and compatibility with various biomolecules make it an indispensable reagent for scientists aiming to innovate in therapeutic and diagnostic fields.

Synonyms
2,5-dioxopyrrolidine-1-yl4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)méthyl)benzoate, 4-Mal-MBz-NHS
CAS Number
64987-84-4
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
MDL Number
MFCD16876288
PubChem ID
13276478
Conditions
Conserver à ≤ -4 °C
General Information
Synonyms
2,5-dioxopyrrolidine-1-yl4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)méthyl)benzoate, 4-Mal-MBz-NHS
CAS Number
64987-84-4
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
MDL Number
MFCD16876288
PubChem ID
13276478
Conditions
Conserver à ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

4-(Maleimidomethyl)-benzoic acid-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to surfaces or other molecules. This is particularly useful in the development of targeted drug delivery systems.
  • Diagnostics: It plays a significant role in the creation of diagnostic tools, including assays and imaging agents, which can help in the early detection of diseases.
  • Protein Labeling: Researchers use this compound to label proteins for various applications, enhancing the study of protein interactions and functions in cellular processes.
  • Therapeutic Development: The compound is valuable in the design of new therapeutics, especially in cancer treatment, where it can facilitate the targeted delivery of drugs to specific cells.
  • Material Science: It is also applied in the development of advanced materials, such as hydrogels and nanomaterials, which have applications in drug release and tissue engineering.

Citations