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Catalog Number:
31646
CAS Number:
64191-06-6
Ester NHS de l'acide 4-maléimidobenzoïque
Synonym(s):
2,5-dioxopyrrolidine-1-yl-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate, 4-Mal-Bz-NHS
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$86.23 /250 mg
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Product Information

4-Maleimidobenzoic acid-NHS ester is a versatile compound widely utilized in bioconjugation and protein labeling applications. This reactive ester is particularly valuable for researchers in the fields of biochemistry and molecular biology, as it facilitates the formation of stable conjugates with proteins, peptides, and other biomolecules. Its unique maleimide functionality allows for selective coupling with thiol groups, making it an ideal choice for creating targeted drug delivery systems and diagnostic agents.

The compound's ability to form covalent bonds under mild conditions enhances its appeal for sensitive biological applications, ensuring that the integrity of the biomolecules is maintained. Additionally, 4-Maleimidobenzoic acid-NHS ester is recognized for its high reactivity and specificity, which can lead to improved performance in assays and therapeutic formulations. Researchers can leverage this compound to develop innovative solutions in areas such as targeted therapy, biomarker discovery, and the development of novel biosensors.

Synonyms
2,5-dioxopyrrolidine-1-yl-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate, 4-Mal-Bz-NHS
CAS Number
64191-06-6
Molecular Formula
C15H10N2O6
Molecular Weight
314.25
MDL Number
MFCD01318593
PubChem ID
9796877
Conditions
Conserver à ≤ -4 °C
General Information
Synonyms
2,5-dioxopyrrolidine-1-yl-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate, 4-Mal-Bz-NHS
CAS Number
64191-06-6
Molecular Formula
C15H10N2O6
Molecular Weight
314.25
MDL Number
MFCD01318593
PubChem ID
9796877
Conditions
Conserver à ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

4-Maleimidobenzoic acid-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link proteins, peptides, or other biomolecules to surfaces or each other, enhancing the development of biosensors and drug delivery systems.
  • Antibody Labeling: It serves as an effective tool for labeling antibodies with fluorophores or other tags, facilitating the study of protein interactions in various biological assays.
  • Drug Development: In pharmaceutical research, it aids in the design of targeted therapies by enabling the conjugation of therapeutic agents to specific cellular targets, improving efficacy and reducing side effects.
  • Diagnostics: The compound is utilized in the creation of diagnostic kits, where it helps in the attachment of biomolecules to solid supports, enhancing the sensitivity and specificity of tests.
  • Material Science: It finds applications in modifying surfaces of materials to improve their biocompatibility, which is crucial for implants and medical devices.

Citations