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Catalog Number:
29776
CAS Number:
1932784-54-7
Acide (2S,5S)-Fmoc-5-méthylpyrrolidine-2-carboxylique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Acide (2S,5S)-1-(9-fluorénylméthyloxycarbonyl)-5-méthyl-pyrrolidine-2-carboxylique, Fmoc-5-méthyl-L-proline (2S,5S), Fmoc-cis-5-méthyl-Pro-OH
Documents
$80.00 /25 mg
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Product Information

The compound (2S,5S)-Fmoc-5-methylpyrrolidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and drug development. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for the selective protection of amino acids during the synthesis process. This compound is particularly valuable in the field of medicinal chemistry, where it facilitates the creation of complex peptide sequences with enhanced stability and bioactivity. Researchers appreciate its ability to streamline the synthesis of peptides, making it an essential tool in the development of pharmaceuticals and biologically active compounds.

In addition to its applications in peptide synthesis, (2S,5S)-Fmoc-5-methylpyrrolidine-2-carboxylic acid is also recognized for its role in the development of novel therapeutic agents. Its favorable properties, such as solubility and reactivity, make it an attractive choice for chemists looking to explore new drug candidates. By incorporating this compound into their research, professionals can enhance the efficiency of their synthetic routes and improve the overall yield of their desired products.

Synonyms
Acide (2S,5S)-1-(9-fluorénylméthyloxycarbonyl)-5-méthyl-pyrrolidine-2-carboxylique, Fmoc-5-méthyl-L-proline (2S,5S), Fmoc-cis-5-méthyl-Pro-OH
CAS Number
1932784-54-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 21 H 214
Molecular Weight
351.4
MDL Number
MFCD28385804
PubChem ID
130156420
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -37 ± 1° (C=1 dans CHCl3)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Acide (2S,5S)-1-(9-fluorénylméthyloxycarbonyl)-5-méthyl-pyrrolidine-2-carboxylique, Fmoc-5-méthyl-L-proline (2S,5S), Fmoc-cis-5-méthyl-Pro-OH
CAS Number
1932784-54-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 21 H 214
Molecular Weight
351.4
MDL Number
MFCD28385804
PubChem ID
130156420
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -37 ± 1° (C=1 dans CHCl3)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(2S,5S)-Fmoc-5-methylpyrrolidine-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide chains essential for drug development.
  • Drug Development: It plays a significant role in the pharmaceutical industry, where it is used to develop new therapeutic agents, especially those targeting neurological disorders, due to its ability to modify peptide structures effectively.
  • Bioconjugation: The compound is utilized in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents, enhancing their specificity and efficacy in targeted therapies.
  • Research in Organic Chemistry: It is a valuable reagent in organic chemistry research, facilitating the study of reaction mechanisms and the development of new synthetic methodologies.
  • Academic Research: This compound is frequently used in academic laboratories for teaching and research purposes, providing students and researchers with hands-on experience in peptide chemistry and synthesis techniques.

Citations