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6-Chloro-4-méthylumbelliféryl β-D-glucuronide
6-Chloro-4-methylumbelliferyl b-D-glucuronide is widely utilized in research focused on:
- Enzyme Activity Assays: This compound serves as a substrate for glucuronidase enzymes, allowing researchers to measure enzyme activity in various biological samples, which is crucial for drug metabolism studies.
- Biochemical Research: It is used in studies investigating glucuronidation, a key metabolic pathway for detoxifying drugs and environmental chemicals, providing insights into pharmacokinetics.
- Fluorescent Probes: The compound exhibits fluorescence upon enzymatic cleavage, making it a valuable tool for visualizing enzyme activity in live cells or tissues, enhancing research in cellular biology.
- Pharmaceutical Development: It aids in the evaluation of drug candidates by assessing their potential for glucuronidation, helping pharmaceutical companies optimize drug formulations for better efficacy and safety.
- Toxicology Studies: The compound is employed in toxicological assessments to evaluate the metabolic pathways of potentially harmful substances, assisting in risk assessment and regulatory compliance.
General Information
Properties
Safety and Regulations
Applications
6-Chloro-4-methylumbelliferyl b-D-glucuronide is widely utilized in research focused on:
- Enzyme Activity Assays: This compound serves as a substrate for glucuronidase enzymes, allowing researchers to measure enzyme activity in various biological samples, which is crucial for drug metabolism studies.
- Biochemical Research: It is used in studies investigating glucuronidation, a key metabolic pathway for detoxifying drugs and environmental chemicals, providing insights into pharmacokinetics.
- Fluorescent Probes: The compound exhibits fluorescence upon enzymatic cleavage, making it a valuable tool for visualizing enzyme activity in live cells or tissues, enhancing research in cellular biology.
- Pharmaceutical Development: It aids in the evaluation of drug candidates by assessing their potential for glucuronidation, helping pharmaceutical companies optimize drug formulations for better efficacy and safety.
- Toxicology Studies: The compound is employed in toxicological assessments to evaluate the metabolic pathways of potentially harmful substances, assisting in risk assessment and regulatory compliance.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
Numéro de catalogue
Numéro de lot/série
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.