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Catalog Number:
23146
CAS Number:
103848-61-9
Acide 6-maléimidocaproïque sulfo-NHS sel de sodium
Purity:
≥ 98 % (HPLC)
Synonym(s):
Sel de sodium de sulfo-EMCS, Ester sulfo- N -succinimidylique de l'acide 6-maléimidocaproïque, sel de sodium
Documents
$396.09 /100 mg
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Product Information

6-Maleimidocaproic acid sulfo-NHS sodium salt is a versatile compound widely utilized in bioconjugation and protein labeling applications. This sulfonated derivative of maleimide is particularly valued for its ability to form stable thioether bonds with thiol-containing biomolecules, making it an essential tool in the development of targeted drug delivery systems and diagnostic assays. Its water-soluble nature enhances its compatibility with various biological systems, facilitating its use in both in vitro and in vivo studies. Researchers appreciate its efficiency in conjugating proteins, peptides, and other biomolecules, which is crucial for creating effective therapeutics and imaging agents.

In addition to its role in bioconjugation, 6-Maleimidocaproic acid sulfo-NHS sodium salt is instrumental in the synthesis of antibody-drug conjugates (ADCs) and other complex biomolecular constructs. Its unique properties allow for precise control over the conjugation process, leading to improved stability and efficacy of the resulting products. This compound stands out among similar reagents due to its enhanced solubility and reactivity, making it a preferred choice for researchers and industry professionals looking to optimize their bioconjugation strategies.

Synonyms
Sel de sodium de sulfo-EMCS, Ester sulfo- N -succinimidylique de l'acide 6-maléimidocaproïque, sel de sodium
CAS Number
103848-61-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C14H16N2O9SNa
Molecular Weight
410.33
MDL Number
MFCD09953186
PubChem ID
4229288
Melting Point
> 250 °C (déc.)
Appearance
Poudre blanche
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Sel de sodium de sulfo-EMCS, Ester sulfo- N -succinimidylique de l'acide 6-maléimidocaproïque, sel de sodium
CAS Number
103848-61-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C14H16N2O9SNa
Molecular Weight
410.33
MDL Number
MFCD09953186
PubChem ID
4229288
Melting Point
> 250 °C (déc.)
Appearance
Poudre blanche
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

6-Maleimidocaproic acid sulfo-NHS sodium salt is widely utilized in research focused on

  • Bioconjugation: This compound is essential for linking proteins, antibodies, or other biomolecules to surfaces or each other, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: It plays a crucial role in creating drug delivery vehicles that can improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Protein Labeling: Researchers use it for labeling proteins with fluorescent tags or other markers, which is vital for studying protein interactions and functions in various biological processes.
  • Diagnostic Assays: The compound is employed in the development of sensitive diagnostic assays, allowing for the detection of biomarkers in diseases, thus facilitating early diagnosis and treatment.
  • Research in Immunology: It is utilized in immunology studies to create conjugates that can enhance immune responses, aiding in vaccine development and understanding immune mechanisms.

Citations