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Catalog Number:
22687
CAS Number:
959581-81-8
3S)-4-Fmoc-1-carboxyméthyl-3-isobutyl-pipérazin-2-one
Purity:
≥ 97 % (HPLC)
Documents
$141.41 /25 mg
Taille
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Product Information

(3S)-4-Fmoc-1-carboxymethyl-3-isobutyl-piperazin-2-one is a versatile compound widely utilized in the field of peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during solid-phase peptide synthesis. Its unique structure not only enhances the stability of the peptide chains but also facilitates the efficient release of the active peptide upon deprotection. Researchers and industry professionals appreciate its role in developing therapeutic peptides, particularly in drug discovery and development processes.

The compound's application extends to the synthesis of complex peptide structures, making it invaluable in the pharmaceutical industry for creating targeted therapies. Its favorable properties, such as high solubility and compatibility with various coupling reagents, allow for streamlined synthesis protocols. Additionally, (3S)-4-Fmoc-1-carboxymethyl-3-isobutyl-piperazin-2-one stands out for its ability to improve yields and purity in peptide synthesis compared to other protecting groups, making it a preferred choice for researchers aiming for efficiency and effectiveness in their projects.

CAS Number
959581-81-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C25H28N2O5
Molecular Weight
436.51
MDL Number
MFCD06656484
PubChem ID
4712613
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +45,0 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
CAS Number
959581-81-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C25H28N2O5
Molecular Weight
436.51
MDL Number
MFCD06656484
PubChem ID
4712613
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +45,0 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(3S)-4-Fmoc-1-carboxymethyl-3-isobutyl-piperazin-2-one is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing researchers to selectively modify amino acids without affecting others. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique structure aids in the design of novel drug candidates, particularly in the field of central nervous system disorders, where piperazine derivatives have shown therapeutic potential.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules to therapeutic agents, enhancing the efficacy and targeting of drugs in cancer treatment.
  • Research in Medicinal Chemistry: It is valuable in medicinal chemistry for studying structure-activity relationships, helping scientists understand how modifications affect biological activity.
  • Analytical Chemistry: This chemical can be employed in analytical methods to detect and quantify specific compounds in biological samples, aiding in drug monitoring and pharmacokinetics studies.

Citations