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Catalog Number:
22638
CAS Number:
917099-02-6
Acide 2R,4S)-Fmoc-4-hydroxypipéridine-2-carboxylique
Purity:
≥ 97 % (HPLC)
Documents
$79.22 /25 mg
Taille
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Product Information

(2R,4S)-Fmoc-4-hydroxypiperidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure allows for the introduction of hydroxyl and carboxylic acid functionalities, making it an ideal candidate for the development of bioactive peptides and pharmaceuticals. Researchers appreciate its stability under various reaction conditions and its compatibility with a range of coupling reagents, which enhances its utility in complex peptide assembly.

In addition to its role in peptide synthesis, (2R,4S)-Fmoc-4-hydroxypiperidine-2-carboxylic acid has potential applications in the development of novel drug candidates targeting various biological pathways. Its ability to facilitate the incorporation of diverse functional groups into peptide sequences opens avenues for the creation of therapeutics with improved efficacy and specificity. This compound stands out for its ease of use and the efficiency it brings to synthetic processes, making it a valuable asset for both academic and industrial researchers focused on peptide-based drug discovery.

CAS Number
917099-02-6
Purity
≥ 97 % (HPLC)
Molecular Formula
C 21 H 215
Molecular Weight
367.4
MDL Number
MFCD06410973
PubChem ID
4712575
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +8,9 ± 1,5º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
CAS Number
917099-02-6
Purity
≥ 97 % (HPLC)
Molecular Formula
C 21 H 215
Molecular Weight
367.4
MDL Number
MFCD06410973
PubChem ID
4712575
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = +8,9 ± 1,5º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(2R,4S)-Fmoc-4-hydroxypiperidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. It enhances the efficiency and yield of peptide production.
  • Drug Development: Its application in medicinal chemistry aids in the design of novel pharmaceutical compounds, particularly those targeting neurological disorders, by modifying the piperidine structure for better bioactivity.
  • Bioconjugation: The compound is used in bioconjugation processes, which are crucial for attaching drugs to antibodies or other biomolecules, improving the specificity and effectiveness of targeted therapies.
  • Material Science: In the development of advanced materials, it contributes to the synthesis of polymers with specific properties, enhancing the performance of materials used in coatings and adhesives.
  • Research Reagents: It acts as a valuable reagent in organic synthesis, facilitating various chemical transformations that are essential for academic and industrial research, particularly in the fields of organic and medicinal chemistry.

Citations