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Catalog Number:
22151
CAS Number:
126-07-8
(+)-Griséofulvine
Purity:
≥ 97 % (HPLC)
Synonym(s):
( 2S )-trans-7-chloro-2',4,6-triméthoxy-6'-méthylspiro(benzofuran-2[3 H] ,1'-[2]cyclohexène)-3,4'-dione
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Product Information

(+)-Griseofulvin is a potent antifungal agent primarily used in the treatment of dermatophyte infections, particularly those affecting the skin, hair, and nails. This compound operates by inhibiting fungal cell division, making it an essential choice for addressing conditions such as ringworm and athlete's foot. Its unique spirocyclic structure contributes to its effectiveness, allowing for targeted action against a broad spectrum of fungal pathogens. Researchers and healthcare professionals appreciate its ability to penetrate keratin-rich tissues, which is crucial for treating infections in hair and nails where other antifungals may fall short.

In addition to its medical applications, (+)-Griseofulvin has potential uses in agricultural settings, particularly in the development of antifungal treatments for crops. Its effectiveness against various fungal strains makes it a valuable candidate for formulating protective agents in agriculture, thereby enhancing crop health and yield. With its established track record and ongoing research into its broader applications, (+)-Griseofulvin remains a compound of interest for both medical and agricultural professionals seeking reliable solutions to fungal challenges.

Synonyms
( 2S )-trans-7-chloro-2',4,6-triméthoxy-6'-méthylspiro(benzofuran-2[3 H] ,1'-[2]cyclohexène)-3,4'-dione
CAS Number
126-07-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C17H17ClO6
Molecular Weight
352.77
MDL Number
MFCD00082343
PubChem ID
3512
Melting Point
218 - 222 ?C
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
350 - 364 ° (C=1, DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
( 2S )-trans-7-chloro-2',4,6-triméthoxy-6'-méthylspiro(benzofuran-2[3 H] ,1'-[2]cyclohexène)-3,4'-dione
CAS Number
126-07-8
Purity
≥ 97 % (HPLC)
Molecular Formula
C17H17ClO6
Molecular Weight
352.77
MDL Number
MFCD00082343
PubChem ID
3512
Melting Point
218 - 222 ?C
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
350 - 364 ° (C=1, DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(+)-Griseofulvin is widely utilized in research focused on

  • Antifungal Treatments: This compound is primarily known for its effectiveness in treating fungal infections, particularly those affecting the skin, hair, and nails. It disrupts fungal cell division, making it a go-to option in dermatology.
  • Veterinary Medicine: Griseofulvin is also used in veterinary practices to manage fungal infections in animals, especially in pets like cats and dogs, ensuring their health and well-being.
  • Research on Fungal Pathogenesis: Researchers utilize this compound to study the mechanisms of fungal infections and resistance, contributing to the development of new antifungal agents and treatment strategies.
  • Pharmaceutical Development: Its unique properties make it a valuable candidate in the formulation of new antifungal medications, allowing pharmaceutical companies to innovate and improve treatment options.
  • Clinical Trials: Griseofulvin is often included in clinical studies to evaluate its efficacy and safety in various populations, providing critical data that informs medical guidelines and treatment protocols.

Citations