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Catalog Number:
21934
CAS Number:
141-90-2
2-Thiouracile
Purity:
≥ 99 % (HPLC)
Synonym(s):
2-Mercapto-4-hydroxypyrimidine
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Product Information

2-Thiouracil is a versatile compound with significant applications in the fields of biochemistry and pharmaceuticals. As a sulfur-containing derivative of uracil, it plays a crucial role in the synthesis of nucleic acids and has been utilized in various research settings to study metabolic pathways and enzyme activities. Its unique structure allows it to act as an effective inhibitor of certain enzymes, making it valuable in the development of therapeutic agents for conditions such as hyperthyroidism. Additionally, 2-Thiouracil has been explored for its potential in cancer research, where it may contribute to the understanding of tumor metabolism and treatment strategies.

Researchers and industry professionals appreciate 2-Thiouracil for its ability to enhance the efficacy of certain drugs and its role in the study of nucleic acid metabolism. Its applications extend to the synthesis of other biologically active compounds, making it a key player in medicinal chemistry. With its established benefits and ongoing research into its properties, 2-Thiouracil remains a compound of interest for those looking to innovate in drug development and biochemical research.

Synonyms
2-Mercapto-4-hydroxypyrimidine
CAS Number
141-90-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H4N2OS
Molecular Weight
128.16
MDL Number
MFCD00006039
PubChem ID
1269845
Melting Point
> 300 °C
Appearance
Poudre blanche
Conditions
Magasin chez RT
General Information
Synonyms
2-Mercapto-4-hydroxypyrimidine
CAS Number
141-90-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H4N2OS
Molecular Weight
128.16
MDL Number
MFCD00006039
PubChem ID
1269845
Melting Point
> 300 °C
Appearance
Poudre blanche
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

2-Thiouracil is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting thyroid disorders. Its ability to inhibit the enzyme thyroperoxidase makes it valuable in creating medications for hyperthyroidism.
  • Biochemical Research: Researchers use 2-Thiouracil to study nucleic acid metabolism and the role of thiol compounds in cellular processes. Its properties allow scientists to investigate the effects of sulfur-containing compounds on RNA and DNA synthesis.
  • Antiviral Applications: The compound has shown potential in antiviral research, particularly against certain viruses. Its mechanism of action can help in the development of new antiviral agents, offering a pathway for innovative treatments.
  • Analytical Chemistry: 2-Thiouracil is employed in various analytical methods to detect and quantify thiol compounds in biological samples. This application is crucial for understanding oxidative stress and related diseases.
  • Education and Training: In academic settings, 2-Thiouracil serves as a model compound for teaching organic synthesis and reaction mechanisms, providing students with hands-on experience in working with sulfur-containing heterocycles.

Citations