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Catalog Number:
14457
CAS Number:
331763-50-9
Acide (4 R ,5 S )-Fmoc-4-amino-5-méthyl-heptanoïque
Purity:
≥ 98 % (HPLC)
Synonym(s):
N- (9-fluorénylméthoxycarbonyl)-γ-L-isoleucine
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$95.24 /100 mg
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Product Information

(4R,5S)-Fmoc-4-amino-5-methyl-heptanoic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is crucial for the selective deprotection of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by a branched aliphatic chain, enhances solubility and stability, making it an ideal choice for researchers focused on developing complex peptides and biologically active compounds.

In the pharmaceutical industry, (4R,5S)-Fmoc-4-amino-5-methyl-heptanoic acid serves as a key intermediate in the synthesis of therapeutic peptides, contributing to advancements in drug formulation and delivery systems. Its application extends to the development of peptide-based vaccines and targeted therapies, where precision and efficacy are paramount. With its favorable properties and practical applications, this compound stands out as a valuable asset for researchers and professionals aiming to innovate in the fields of biochemistry and medicinal chemistry.

Synonyms
N- (9-fluorénylméthoxycarbonyl)-γ-L-isoleucine
CAS Number
331763-50-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C 23 H 274
Molecular Weight
381.47
MDL Number
MFCD02094560
PubChem ID
4712545
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 10,3 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
N- (9-fluorénylméthoxycarbonyl)-γ-L-isoleucine
CAS Number
331763-50-9
Purity
≥ 98 % (HPLC)
Molecular Formula
C 23 H 274
Molecular Weight
381.47
MDL Number
MFCD02094560
PubChem ID
4712545
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 10,3 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

(4R,5S)-Fmoc-4-amino-5-methyl-heptanoic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective Fmoc group allows for selective deprotection, making it easier to assemble complex peptide chains.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The ability to modify the amino acid structure enhances the efficacy and specificity of therapeutic agents, particularly in targeting diseases like cancer.
  • Bioconjugation: This chemical is employed in bioconjugation processes to attach peptides to other molecules, such as antibodies or drugs. This application is crucial in developing targeted therapies and improving drug delivery systems.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their stability and activity. This is particularly beneficial in the development of enzymes and therapeutic proteins for industrial and medical applications.
  • Research in Neuroscience: It is also used in the synthesis of neuropeptides, which play significant roles in brain function. This application aids in understanding neurological disorders and developing potential treatments.

Citations