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Catalog Number:
21701
CAS Number:
1184-43-6
Chlorure de tétrazolium tétranitrobleu
Purity:
≥ 90 % (dosage)
Synonym(s):
Chlorure de 2,2',5,5'-tétra(4-nitrophényl)-3,3'-diméthoxy-4,4'-biphénylène-2H,2H'-ditétrazolium, TNBT
Documents
$65.00 /100 mg
Taille
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Informations sur le produit

Tetranitroblue tetrazolium chloride is a versatile chemical compound widely recognized for its application in biochemical assays, particularly in the field of cell viability and cytotoxicity testing. This compound serves as an effective electron acceptor, facilitating the reduction of tetrazolium salts to formazan crystals, which can be quantitatively measured. Its ability to provide a colorimetric readout makes it invaluable in laboratories for assessing cellular metabolic activity, thus aiding researchers in drug development and toxicology studies.

Moreover, Tetranitroblue tetrazolium chloride is utilized in histochemistry for visualizing enzyme activity, particularly in the detection of dehydrogenases. Its unique properties allow for clear differentiation in tissue samples, enhancing the understanding of various biological processes. With its high sensitivity and specificity, this compound stands out as a reliable choice for professionals seeking accurate and reproducible results in their research endeavors.

Numéro CAS 
1184-43-6
Formule moléculaire
C40H28N12O10 · 2Cl
Poids moléculaire 
907.64
Point de fusion 
169 - 171 °C
Informations générales
Numéro CAS 
1184-43-6
Formule moléculaire
C40H28N12O10 · 2Cl
Poids moléculaire 
907.64
Point de fusion 
169 - 171 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Tetranitroblue tetrazolium chloride is widely utilized in research focused on:

  • Biochemical Assays: This compound is commonly used in cell viability assays, such as the MTT assay, where it helps to assess the metabolic activity of living cells. This is crucial in drug development and toxicity testing.
  • Histological Staining: It serves as a vital reagent in histology for staining tissues, particularly in identifying the presence of certain enzymes. This application is essential in pathology and medical research.
  • Electrochemical Studies: The compound is employed in electrochemical sensors for detecting various biomolecules, enhancing the sensitivity and specificity of these devices, which is invaluable in clinical diagnostics.
  • Nanotechnology: It is utilized in the synthesis of nanoparticles, particularly in the development of drug delivery systems, offering targeted therapy options in cancer treatment.
  • Environmental Monitoring: Tetranitroblue tetrazolium chloride is used in assessing the toxicity of pollutants in environmental samples, aiding in ecological studies and regulatory compliance.

Citations