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Catalog Number:
42195
CAS Number:
196309-76-9
BAIE 11-7085
Purity:
≥ 98 % (HPLC)
Synonym(s):
( E -3-(4- tert -butylphénylsulfonyl)acrylonitrile
Documents
$134.70 /10 mg
Taille
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Informations sur le produit

BAY 11-7085 is a potent and selective inhibitor of the NF-kB signaling pathway, making it a valuable tool in both research and therapeutic applications. This compound is recognized for its ability to modulate inflammatory responses and has been extensively studied for its potential in cancer research, where it may help in reducing tumor growth and metastasis. Researchers have utilized BAY 11-7085 to explore its effects on various cell lines, demonstrating its efficacy in inhibiting cell proliferation and inducing apoptosis in cancer cells. Additionally, its role in neuroprotection and as a potential treatment for neurodegenerative diseases has garnered attention, highlighting its versatility in biomedical research.

With its unique sulfonylprop-2-enenitrile structure, BAY 11-7085 offers advantages over other NF-kB inhibitors, such as enhanced specificity and reduced off-target effects. This makes it an ideal candidate for studies focused on inflammatory diseases, autoimmune disorders, and cancer therapy. Its ability to effectively block NF-kB activation positions BAY 11-7085 as a crucial compound for researchers aiming to develop targeted therapies and understand the underlying mechanisms of disease.

Numéro CAS 
196309-76-9
Formule moléculaire
C 13 H 15 NO 2 S
Poids moléculaire 
249.33
Point de fusion 
82 - 86 °C
Informations générales
Numéro CAS 
196309-76-9
Formule moléculaire
C 13 H 15 NO 2 S
Poids moléculaire 
249.33
Point de fusion 
82 - 86 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

BAY 11-7085 is widely utilized in research focused on:

  • Inflammation Studies: This compound is known for its ability to inhibit NF-kB activation, making it valuable in studies aimed at understanding inflammatory diseases and potential therapeutic interventions.
  • Cancer Research: Researchers use BAY 11-7085 to explore its effects on cancer cell proliferation and survival, particularly in studies targeting tumor growth and metastasis.
  • Neuroscience Applications: The compound has been investigated for its neuroprotective properties, offering insights into treatments for neurodegenerative diseases.
  • Drug Development: Its unique mechanism of action provides a basis for developing new anti-inflammatory and anticancer drugs, helping to address the limitations of existing therapies.
  • Cell Signaling Pathway Analysis: BAY 11-7085 is used in experiments to dissect various signaling pathways, aiding in the understanding of cellular responses to stress and injury.

Citations