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Catalog Number:
38826
CAS Number:
133073-73-1
Méthotrexate hydraté
Grade:
adapté à la culture cellulaire
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide 4-amino-10-méthylfolique hydraté, L-améthoptérine hydratée
Hazmat
Documents
$247.77 /100 mg
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Informations sur le produit

Methotrexate hydrate is a potent antimetabolite and antifolate agent widely utilized in the treatment of various cancers and autoimmune diseases. This compound functions by inhibiting dihydrofolate reductase, thereby disrupting DNA synthesis and cellular replication. Its applications extend beyond oncology, as it is also employed in the management of conditions such as rheumatoid arthritis and psoriasis, showcasing its versatility in therapeutic settings. Researchers and healthcare professionals value Methotrexate hydrate for its efficacy in combination therapies, enhancing the effectiveness of other treatments while minimizing side effects.

In addition to its established medical uses, Methotrexate hydrate is a subject of ongoing research, exploring its potential in novel therapeutic strategies and drug formulations. Its unique properties, including solubility and stability, make it an ideal candidate for pharmaceutical development. With a strong track record in clinical applications, Methotrexate hydrate continues to be a critical component in the arsenal against malignancies and chronic inflammatory diseases, offering significant benefits to patients and healthcare providers alike.

Numéro CAS 
133073-73-1
Formule moléculaire
C20H22N8O5 · xH2O
Poids moléculaire 
454.44
Informations générales
Numéro CAS 
133073-73-1
Formule moléculaire
C20H22N8O5 · xH2O
Poids moléculaire 
454.44
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Methotrexate hydrate is widely utilized in research focused on:

  • Cancer Treatment: This compound is a cornerstone in chemotherapy, particularly for treating various types of cancers such as leukemia and lymphoma. Its ability to inhibit cell growth makes it effective in targeting rapidly dividing cancer cells.
  • Autoimmune Disorders: Methotrexate is commonly prescribed for conditions like rheumatoid arthritis and psoriasis. It helps reduce inflammation and suppress the immune system, providing relief to patients.
  • Research in Biochemistry: In laboratory settings, it is used to study metabolic pathways and enzyme activity. Researchers utilize it to understand folate metabolism and its implications in cellular processes.
  • Pharmaceutical Development: The compound serves as a model for developing new drugs. Its mechanism of action provides insights into designing more effective therapies with fewer side effects.
  • Veterinary Medicine: Methotrexate is also applied in treating certain cancers and autoimmune diseases in animals, showcasing its versatility beyond human medicine.

Citations