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Catalog Number:
37565
CAS Number:
446-86-6
Azathioprine
Purity:
≥ 98 % (dosage par titration, HPLC)
Synonym(s):
6-(1-méthyl-4-nitroimidazol-5-yl)thiopurine
Documents
$181.67 /5G
Taille
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Informations sur le produit

Azathioprine is a potent immunosuppressive agent widely utilized in the treatment of autoimmune diseases and organ transplantation. This compound functions by inhibiting the proliferation of lymphocytes, making it invaluable in managing conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease. Its unique mechanism of action allows for the modulation of the immune response, thereby reducing the risk of organ rejection in transplant patients.

In addition to its therapeutic applications, Azathioprine is also employed in research settings to study immune system functions and the effects of immunosuppression. Its ability to selectively target rapidly dividing cells makes it a critical tool in both clinical and laboratory environments. Researchers appreciate its versatility and effectiveness, particularly in combination therapies, where it can enhance the efficacy of other immunosuppressive agents. With a well-established safety profile and a history of successful application, Azathioprine remains a cornerstone in the management of various immune-mediated conditions.

Numéro CAS 
446-86-6
Formule moléculaire
C9H7N7O2S
Poids moléculaire 
277.26
Point de fusion 
244 °C (déc.)
Informations générales
Numéro CAS 
446-86-6
Formule moléculaire
C9H7N7O2S
Poids moléculaire 
277.26
Point de fusion 
244 °C (déc.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Azathioprine is widely utilized in research focused on

  • Autoimmune Disorders: It is commonly prescribed to manage conditions like rheumatoid arthritis and lupus, helping to suppress the immune system and reduce inflammation.
  • Organ Transplantation: Azathioprine plays a crucial role in preventing organ rejection by inhibiting the immune response, making it essential for transplant patients.
  • Cancer Treatment: In oncology, it is used as a chemotherapeutic agent for certain types of leukemia and other malignancies, providing an alternative to more aggressive treatments.
  • Research in Immunology: Scientists utilize azathioprine to study immune system functions and develop new therapies, contributing to advancements in immunotherapy.
  • Cost-Effectiveness: Compared to newer immunosuppressants, azathioprine offers a more affordable option for long-term treatment, making it accessible for many patients.

Citations