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Catalog Number:
37923
CAS Number:
184475-35-2
Géfitinib
Purity:
≥ 99 % (HPLC)
Synonym(s):
N- (3-chloro-4-fluorophényl)-7-méthoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Documents
$20.00 /1G
Taille
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Informations sur le produit

Gefitinib is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, primarily used in the treatment of non-small cell lung cancer (NSCLC). This compound has gained significant attention in oncology due to its ability to block the signaling pathways that promote tumor growth and survival, making it a critical therapeutic agent for patients with specific EGFR mutations. Researchers and healthcare professionals appreciate Gefitinib for its targeted action, which minimizes damage to healthy cells compared to traditional chemotherapy, thereby enhancing patient quality of life during treatment.

In addition to its primary application in cancer therapy, Gefitinib is also being explored in combination with other agents to improve treatment outcomes in various malignancies. Its unique chemical structure allows for effective binding to the EGFR, providing a clear advantage over non-selective treatments. As ongoing studies continue to reveal its potential in personalized medicine, Gefitinib remains a valuable compound in the pharmaceutical landscape, offering hope for improved survival rates and better management of lung cancer.

Numéro CAS 
184475-35-2
Formule moléculaire
C22H24ClFN4O3
Poids moléculaire 
446.91
Point de fusion 
194 - 198 °C (lit.)
Informations générales
Numéro CAS 
184475-35-2
Formule moléculaire
C22H24ClFN4O3
Poids moléculaire 
446.91
Point de fusion 
194 - 198 °C (lit.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Gefitinib is widely utilized in research focused on:

  • Targeted Cancer Therapy: Primarily used in the treatment of non-small cell lung cancer (NSCLC), Gefitinib inhibits specific growth factor receptors, leading to reduced tumor growth and improved patient outcomes.
  • Personalized Medicine: Its application in genetic testing allows healthcare providers to tailor treatments based on the presence of specific mutations in patients, enhancing treatment efficacy and minimizing side effects.
  • Combination Therapy Research: Researchers are exploring Gefitinib's effectiveness when combined with other cancer treatments, potentially improving overall survival rates and reducing resistance in cancer cells.
  • Pharmaceutical Development: The compound serves as a model for developing new anti-cancer drugs, providing insights into drug design and the mechanisms of action against similar tumors.
  • Clinical Trials: Gefitinib is frequently involved in clinical studies aimed at understanding its long-term effects and potential benefits in various cancer types, contributing to the advancement of oncological therapies.

Citations