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Catalog Number:
37983
CAS Number:
65277-42-1
Kétoconazole
Grade:
Conforme aux spécifications USP
Purity:
98 - 102 % (dosage sur une base sèche)
Synonym(s):
(+/-)- cis -1-acétyl-4-[4-[[2-(2,4-dichlorophényl)-2-(imidazol-1-ylméthyl)-1,3-dioxolan-4-yl]méthoxy]phényl]pipérazine
Hazmat
Documents
$18.50 /25G
Taille
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Informations sur le produit

Ketoconazole is a broad-spectrum antifungal agent widely recognized for its effectiveness in treating various fungal infections. This compound is particularly valuable in dermatology, where it is used to manage conditions such as seborrheic dermatitis, tinea infections, and candidiasis. Its mechanism of action involves inhibiting ergosterol synthesis, a crucial component of fungal cell membranes, which leads to cell death and the resolution of infections. Ketoconazole is available in various formulations, including topical creams, shampoos, and oral tablets, making it versatile for both local and systemic treatment.

In addition to its antifungal properties, Ketoconazole has shown potential in treating certain skin disorders and conditions related to excessive sebum production. Researchers are exploring its applications in the management of conditions like acne and psoriasis, highlighting its relevance in both therapeutic and cosmetic formulations. With its proven efficacy and broad application range, Ketoconazole remains a key compound in the pharmaceutical and healthcare industries, offering significant benefits to both patients and healthcare providers.

Numéro CAS 
65277-42-1
Formule moléculaire
C26H28Cl2N4O4
Poids moléculaire 
531.43
Point de fusion 
150 - 155 °C (lit.)
Rotation optique 
[a] D 20 = -1 à 1 ° (C = 40 mg/mL dans le méthanol)
Informations générales
Numéro CAS 
65277-42-1
Formule moléculaire
C26H28Cl2N4O4
Poids moléculaire 
531.43
Point de fusion 
150 - 155 °C (lit.)
Rotation optique 
[a] D 20 = -1 à 1 ° (C = 40 mg/mL dans le méthanol)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Ketoconazole is widely utilized in research focused on:

  • Antifungal Treatments: Commonly used in dermatology, ketoconazole is effective against various fungal infections, such as athlete's foot and ringworm, providing relief and promoting skin health.
  • Shampoos for Scalp Conditions: Incorporated into medicated shampoos, it helps treat dandruff and seborrheic dermatitis by reducing fungal growth on the scalp, improving overall hair and scalp condition.
  • Hormonal Imbalance Management: In endocrinology, ketoconazole is used to manage conditions like Cushing's syndrome by inhibiting cortisol production, assisting patients in regulating hormone levels.
  • Research in Drug Development: As a model compound, it aids in the study of antifungal mechanisms and resistance, helping researchers develop more effective antifungal agents.
  • Veterinary Medicine: Utilized in treating fungal infections in animals, ketoconazole supports veterinary professionals in managing pet health, particularly for skin and systemic fungal issues.

Citations