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Catalog Number:
38729
CAS Number:
143-62-4
Digitoxigénine
Purity:
≥ 95 % (dosage sur une base sèche)
Synonym(s):
3β,14-Dihydroxy-5β,20(22)-cardénolide, Acide 3,14,21-trihydroxy-20(22)-norcholénique lactone
Hazmat
Documents
$130.00 /10 mg
Taille
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Informations sur le produit

Digitoxigenin is a naturally occurring cardiac glycoside that plays a significant role in the field of pharmacology, particularly in the development of treatments for heart conditions. This compound is recognized for its ability to enhance cardiac contractility, making it valuable in the management of heart failure and arrhythmias. Its unique structure allows it to interact effectively with sodium-potassium ATPase, leading to increased intracellular calcium levels, which is crucial for improving heart muscle function.

In addition to its therapeutic applications, Digitoxigenin is also utilized in research settings to study the mechanisms of cardiac glycosides and their effects on cellular processes. Its potential as a lead compound for developing new cardiovascular drugs is noteworthy, as it offers a foundation for synthesizing derivatives with improved efficacy and reduced side effects. Researchers and industry professionals can leverage Digitoxigenin's properties to explore innovative treatments and enhance existing therapies in cardiology.

Numéro CAS 
143-62-4
Formule moléculaire
C23H34O4
Poids moléculaire 
374.52
Point de fusion 
253 ?C
Rotation optique 
[a]20D = 15 - 20 ° (C = 1 dans MeOH)
Informations générales
Numéro CAS 
143-62-4
Formule moléculaire
C23H34O4
Poids moléculaire 
374.52
Point de fusion 
253 ?C
Rotation optique 
[a]20D = 15 - 20 ° (C = 1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Digitoxigenin is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is a key precursor in the synthesis of cardiac glycosides, which are used to treat heart conditions such as atrial fibrillation and heart failure.
  • Biochemical Research: It serves as a valuable tool in studies investigating the mechanisms of action of steroid hormones and their effects on cellular processes.
  • Natural Product Chemistry: Researchers use digitoxigenin to explore the biosynthesis of plant-derived compounds, enhancing our understanding of natural product pathways.
  • Toxicology Studies: Its role in evaluating the toxicity of cardiac glycosides helps in assessing safety profiles for new drug formulations.
  • Pharmacognosy: This compound is studied for its potential therapeutic effects and benefits in traditional medicine, particularly in herbal remedies.

Citations