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Catalog Number:
22123
CAS Number:
59865-13-3
Cyclosporine A
Grade:
USP
Purity:
97,0 - 101,5 % (dosage, sur une base sèche)
Synonym(s):
Cyclosporine
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Informations sur le produit

Cyclosporin A is a potent immunosuppressant widely recognized for its critical role in organ transplantation and autoimmune disease management. This cyclic peptide, derived from the fungus Tolypocladium inflatum, is particularly effective in preventing organ rejection in transplant patients by inhibiting T-cell activation and proliferation. Its unique mechanism of action makes it invaluable in clinical settings, allowing for improved graft survival rates and enhanced patient outcomes. Beyond transplantation, Cyclosporin A is also utilized in treating conditions such as rheumatoid arthritis and psoriasis, showcasing its versatility in therapeutic applications.

In addition to its medical uses, Cyclosporin A has garnered attention in research for its potential in studying cellular signaling pathways and immune responses. Its ability to modulate immune function opens avenues for innovative treatments in various fields, including oncology and chronic inflammatory diseases. Researchers appreciate Cyclosporin A not only for its efficacy but also for its relatively favorable safety profile compared to other immunosuppressants, making it a preferred choice in many therapeutic regimens.

Numéro CAS 
59865-13-3
Formule moléculaire
C 62 H 111 N 11 O 12
Poids moléculaire 
1202.64
Informations générales
Numéro CAS 
59865-13-3
Formule moléculaire
C 62 H 111 N 11 O 12
Poids moléculaire 
1202.64
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Cyclosporin A is widely utilized in research focused on:

  • Organ Transplantation: It is a critical immunosuppressant used to prevent organ rejection in transplant patients, helping to improve survival rates and quality of life.
  • Autoimmune Diseases: This compound is effective in treating conditions like rheumatoid arthritis and psoriasis by modulating the immune response, offering relief to patients.
  • Research in Immunology: Cyclosporin A serves as a valuable tool in studying immune system functions and mechanisms, aiding researchers in developing new therapies.
  • Dermatology: It is used in topical formulations for skin conditions, providing targeted treatment with fewer systemic side effects compared to oral medications.
  • Pharmaceutical Development: The compound is often used as a reference standard in drug formulation studies, ensuring the efficacy and safety of new medications.

Citations