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Catalog Number:
38471
CAS Number:
50-76-0
Actinomycine D de l'espèce Streptomyces
Grade:
adapté à la culture cellulaire
Purity:
≥ 95 % (HPLC)
Synonym(s):
Dactinomycin, Actinomycine C1
Hazmat
Documents
$38.46 /5 mg
Taille
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Informations sur le produit
Numéro CAS 
50-76-0
Formule moléculaire
C 62 H 86 N 12 O 16
Poids moléculaire 
0
Point de fusion 
243 - 248 °C
Rotation optique 
[a] 20 D = -292 à -317 °
Informations générales
Numéro CAS 
50-76-0
Formule moléculaire
C 62 H 86 N 12 O 16
Poids moléculaire 
0
Point de fusion 
243 - 248 °C
Rotation optique 
[a] 20 D = -292 à -317 °
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Actinomycin D from Streptomyces species is widely utilized in research focused on:

  • Cancer Treatment: This compound is a potent anti-cancer agent, commonly used in chemotherapy regimens for various types of tumors, including Wilms' tumor and rhabdomyosarcoma, providing effective treatment options for patients.
  • Gene Expression Studies: Researchers employ Actinomycin D to inhibit RNA synthesis, allowing them to study gene expression and regulation mechanisms in cellular biology, which is crucial for understanding diseases.
  • Antibiotic Development: Its unique structure and mechanism of action inspire the development of new antibiotics, making it a valuable compound in the fight against antibiotic-resistant bacteria.
  • Cell Cycle Research: Actinomycin D is used to investigate the effects of transcriptional inhibition on cell cycle progression, helping scientists understand cellular responses to stress and potential therapeutic targets.
  • Biotechnology Applications: In biomanufacturing, it serves as a tool for optimizing the production of recombinant proteins by controlling gene expression, enhancing yield and efficiency in industrial processes.

Citations