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Catalog Number:
38146
CAS Number:
144689-24-7
Olmésartan
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide 4-(1-hydroxy-1-méthyléthyl)-2-propyl-1-[[2'-(2 H -tétrazol-5-yl)[1,1'-biphényl]-4-yl]méthyl]-1 H -imidazole-5-carboxylique, Acide olmésartan
Documents
$174.96 /100 mg
Taille
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Informations sur le produit

Olmesartan is a potent angiotensin II receptor antagonist primarily used in the treatment of hypertension. This compound works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and lowering blood pressure. Its unique structure, featuring a tetrazole ring, enhances its binding affinity and selectivity for the angiotensin receptor, making it a preferred choice for managing high blood pressure in patients who may not respond adequately to other antihypertensive agents.

In addition to its primary use in hypertension, Olmesartan has shown potential benefits in reducing the risk of cardiovascular events and improving renal outcomes in patients with diabetes. Its favorable pharmacokinetic profile allows for once-daily dosing, improving patient compliance. Researchers and healthcare professionals appreciate Olmesartan for its efficacy and safety profile, making it a valuable addition to the therapeutic arsenal against cardiovascular diseases.

Numéro CAS 
144689-24-7
Formule moléculaire
C24H26N6O3
Poids moléculaire 
446.51
Point de fusion 
177 °C (déc.)
Informations générales
Numéro CAS 
144689-24-7
Formule moléculaire
C24H26N6O3
Poids moléculaire 
446.51
Point de fusion 
177 °C (déc.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Olmesartan is widely utilized in research focused on:

  • Hypertension Management: It is primarily used as an antihypertensive agent to treat high blood pressure, helping to reduce the risk of heart disease and stroke.
  • Cardiovascular Research: Researchers explore its effects on cardiovascular health, studying how it can improve heart function and reduce complications associated with hypertension.
  • Diabetes-Related Studies: Olmesartan is investigated for its potential benefits in diabetic patients, particularly in protecting kidney function and reducing the risk of diabetic nephropathy.
  • Combination Therapies: It is often used in combination with other antihypertensive medications, allowing for more effective blood pressure control with potentially fewer side effects.
  • Pharmacological Research: Ongoing studies focus on its mechanism of action and long-term effects, contributing to the development of new treatment protocols for hypertension and related conditions.

Citations