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Catalog Number:
38099
CAS Number:
66085-59-4
Nimodipine
Purity:
≥ 98 % (HPLC)
Synonym(s):
2-méthoxyéthyl1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylate d'isopropyle, Ester 2-méthoxyéthylique et 1-méthyléthylique de l'acide 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylique
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Taille
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Informations sur le produit

Nimodipine is a potent calcium channel blocker primarily used in the medical field for its ability to improve cerebral blood flow. This compound is particularly effective in the treatment of subarachnoid hemorrhage, where it helps prevent vasospasm and enhances neurological outcomes. Its unique structure allows for selective action on cerebral blood vessels, making it a valuable asset in neuroprotective therapies. Researchers and healthcare professionals appreciate Nimodipine for its efficacy in managing conditions related to impaired blood flow, and its application extends to studies investigating its potential benefits in various neurological disorders.

In addition to its clinical applications, Nimodipine is also of interest in pharmaceutical research for developing novel formulations aimed at enhancing bioavailability and therapeutic efficacy. Its favorable pharmacokinetic profile and ability to cross the blood-brain barrier make it a candidate for further exploration in drug delivery systems. As a result, Nimodipine stands out not only for its established medical uses but also for its potential in advancing therapeutic strategies in neurology.

Numéro CAS 
66085-59-4
Formule moléculaire
C21H26N2O7
Poids moléculaire 
418.45
Point de fusion 
124 - 128 °C
Informations générales
Numéro CAS 
66085-59-4
Formule moléculaire
C21H26N2O7
Poids moléculaire 
418.45
Point de fusion 
124 - 128 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Nimodipine is widely utilized in research focused on:

  • Treatment of Subarachnoid Hemorrhage: Nimodipine is primarily used in clinical settings to improve outcomes in patients who have suffered a subarachnoid hemorrhage, helping to prevent complications such as vasospasm.
  • Neuroprotection: Researchers explore its neuroprotective properties, which may benefit conditions like stroke and traumatic brain injury by improving blood flow to the brain.
  • Cardiovascular Research: The compound is studied for its effects on vascular smooth muscle, making it relevant in research on hypertension and other cardiovascular diseases.
  • Pharmaceutical Development: Nimodipine serves as a model compound in drug formulation studies, particularly in the development of sustained-release formulations due to its unique pharmacokinetic profile.
  • Investigating Calcium Channel Blockers: It is commonly used in studies examining the role of calcium channel blockers in various physiological and pathological processes, providing insights into their therapeutic potential.

Citations