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Catalog Number:
37961
CAS Number:
148849-67-6
Chlorhydrate d'ivabradine
Purity:
≥ 98 % (HPLC)
Documents
$237.46 /200 mg
Taille
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Informations sur le produit

Ivabradine hydrochloride is a selective heart rate-lowering agent primarily used in the treatment of chronic stable angina and heart failure. This compound acts by inhibiting the If current in the sinoatrial node, leading to a reduction in heart rate without affecting myocardial contractility. Its unique mechanism of action makes it particularly beneficial for patients who cannot tolerate beta-blockers or for those who require additional heart rate control.

In clinical settings, Ivabradine hydrochloride has demonstrated efficacy in improving exercise tolerance and quality of life for patients with coronary artery disease. Its ability to specifically target heart rate regulation while minimizing side effects associated with traditional therapies positions it as a valuable option in cardiovascular treatment protocols. Researchers and healthcare professionals appreciate its role in managing heart conditions, making it a significant compound in the pharmaceutical landscape.

Numéro CAS 
148849-67-6
Formule moléculaire
C27H36N2O5 · HCl
Poids moléculaire 
505.05
Point de fusion 
139 - 141 °C
Rotation optique 
[a] 20 D = 6,0 - 8,5 ° (C=1, DMSO)
Informations générales
Numéro CAS 
148849-67-6
Formule moléculaire
C27H36N2O5 · HCl
Poids moléculaire 
505.05
Point de fusion 
139 - 141 °C
Rotation optique 
[a] 20 D = 6,0 - 8,5 ° (C=1, DMSO)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Ivabradine hydrochloride is widely utilized in research focused on

  • Cardiovascular Medicine: Primarily used to treat chronic heart failure and angina, it helps to lower heart rate without affecting blood pressure, making it a valuable option for patients with specific heart conditions.
  • Clinical Trials: Frequently involved in clinical studies to assess its efficacy and safety in various populations, providing critical data for healthcare professionals and researchers.
  • Pharmaceutical Development: Used in the formulation of new medications aimed at managing cardiovascular diseases, contributing to advancements in patient care and treatment options.
  • Research on Heart Rate Regulation: Serves as a tool in studies investigating the mechanisms of heart rate control, aiding researchers in understanding cardiac physiology and potential therapeutic targets.
  • Combination Therapies: Explored in combination with other cardiovascular drugs to enhance treatment outcomes, offering a synergistic approach to managing complex heart conditions.

Citations