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Catalog Number:
35066
CAS Number:
1480516-75-3
DBCO-PEG 4 -maléimide
Purity:
≥ 98 % (HPLC)
Synonym(s):
Dibenzocyclooctyne-PEG4-maléimide
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$140.20 /5 mg
Taille
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Informations sur le produit

DBCO-PEG4-maleimide is a versatile compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique structure that allows for efficient and selective coupling with thiol-containing biomolecules, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its PEG4 linker enhances solubility and biocompatibility, facilitating the development of stable conjugates that can be used in therapeutic and diagnostic applications.

In practical terms, DBCO-PEG4-maleimide is particularly valuable in the creation of antibody-drug conjugates (ADCs), where it can be employed to attach cytotoxic drugs to antibodies, thereby improving the targeted delivery of therapeutics to cancer cells. Additionally, it is used in the development of fluorescent probes for imaging applications, allowing for real-time tracking of biological processes. The compound's ability to form stable conjugates while maintaining biological activity makes it a preferred choice for researchers looking to enhance the efficacy of their biomolecular constructs.

Numéro CAS 
1480516-75-3
Formule moléculaire
C 36 H 42 N 4 O 9
Poids moléculaire 
674.74
Informations générales
Numéro CAS 
1480516-75-3
Formule moléculaire
C 36 H 42 N 4 O 9
Poids moléculaire 
674.74
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

DBCO-PEG4-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to various targets. Its unique reactivity allows for precise conjugation, enhancing the efficacy of therapeutic agents.
  • Drug Delivery Systems: DBCO-PEG4-maleimide is used in the development of advanced drug delivery systems. By attaching drugs to this compound, researchers can improve the solubility and stability of pharmaceuticals, leading to better patient outcomes.
  • Diagnostics: In the field of diagnostics, this chemical aids in the creation of imaging agents. Its ability to form stable linkages with imaging probes enhances the sensitivity and specificity of diagnostic tests.
  • Nanotechnology: DBCO-PEG4-maleimide plays a crucial role in the fabrication of nanoparticles for targeted therapy. Its properties allow for the customization of nanoparticles, making them effective carriers for targeted drug delivery.
  • Research and Development: This compound is widely used in academic and industrial research settings for developing new materials and studying biological processes. Its versatility makes it a valuable tool for scientists exploring innovative applications.

Citations