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Catalog Number:
41704
Ester de méthyle-PEG 12 -NHS
Synonym(s):
N- Succinimidyl-4,7,10,13,16,19,22,25,28,31,34,37-dodécaoxaoctatriacontanoate, Ester N -succinimidylique de l'acide 4,7,10,13,16,19,22,25,28,31,34,37-dodécaoxaoctatriacontanoïque, Ester mPEG12-NHS
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$283.93 /25 mg
Taille
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Informations sur le produit

Methyl-PEG12-NHS ester is a versatile and highly functional reagent widely utilized in bioconjugation and drug delivery applications. This compound features a polyethylene glycol (PEG) backbone, which enhances solubility and biocompatibility, making it an ideal choice for researchers and industry professionals looking to improve the pharmacokinetics of therapeutic agents. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling to amine-containing biomolecules, facilitating the formation of stable linkages in various bioconjugation processes.

This compound is particularly beneficial in the development of antibody-drug conjugates (ADCs) and other targeted therapies, where precise control over the drug-to-antibody ratio is crucial for efficacy and safety. Additionally, Methyl-PEG12-NHS ester can be employed in the creation of functionalized surfaces for biosensors and drug delivery systems, enhancing the performance and specificity of these applications. Its unique properties make it a valuable tool in the fields of pharmaceuticals, biotechnology, and materials science, providing researchers with the means to innovate and optimize their projects effectively.

Formule moléculaire
C 30 H 5516
Poids moléculaire 
685.76
Informations générales
Formule moléculaire
C 30 H 5516
Poids moléculaire 
685.76
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Methyl-PEG12-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the stability and functionality of therapeutic agents.
  • Drug Delivery Systems: Its properties allow for the creation of advanced drug delivery systems, improving the solubility and bioavailability of poorly soluble drugs, which is crucial in pharmaceutical development.
  • Diagnostics: Methyl-PEG12-NHS ester plays a significant role in the development of diagnostic assays by facilitating the attachment of detection molecules to surfaces, thereby increasing sensitivity and accuracy.
  • Surface Modification: This chemical is used to modify surfaces of medical devices and implants, reducing protein adsorption and improving biocompatibility, which is essential for patient safety.
  • Research Applications: It is frequently employed in various research settings to create customized materials for studying cellular interactions and drug responses, providing valuable insights into biological processes.

Citations