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Catalog Number:
35051
CAS Number:
1427004-19-0
Ester de DBCO-PEG 4 -NHS
Purity:
≥ 95 % (RMN)
Synonym(s):
Ester de dibenzocyclooctyne-PEG4-NHS
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$140.00 /5 mg
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Informations sur le produit

DBCO-PEG4-NHS ester is a versatile and highly functional compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique combination of a DBCO (dibenzocyclooctyne) moiety and a PEG4 (polyethylene glycol) linker, which enhances solubility and biocompatibility. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling to amine-containing biomolecules, making it an ideal choice for researchers looking to create stable conjugates for therapeutic and diagnostic purposes.

In the field of biochemistry, DBCO-PEG4-NHS ester is particularly valuable for labeling proteins, antibodies, and other biomolecules, facilitating the development of targeted drug delivery systems and imaging agents. Its ability to form stable covalent bonds with various substrates enables the creation of complex biomolecular constructs, which can significantly improve the efficacy of therapeutic agents. Additionally, the PEG component contributes to reduced immunogenicity and enhanced circulation time in vivo, making this compound a preferred choice for innovative drug formulation strategies.

Numéro CAS 
1427004-19-0
Formule moléculaire
C34H39N3O10
Poids moléculaire 
649.68
Informations générales
Numéro CAS 
1427004-19-0
Formule moléculaire
C34H39N3O10
Poids moléculaire 
649.68
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

DBCO-PEG4-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its ability to form stable linkages makes it ideal for creating advanced drug delivery systems, allowing for controlled release of therapeutics in specific tissues, improving treatment efficacy.
  • Fluorescent Labeling: Researchers use DBCO-PEG4-NHS ester to label biomolecules with fluorescent tags, facilitating real-time tracking of biological processes in live cells, which is crucial for understanding cellular functions.
  • Surface Modification: This ester is employed to modify surfaces of materials in biosensors, enhancing their sensitivity and specificity for detecting biomolecules, which is vital in medical diagnostics.
  • Polymer Chemistry: In the field of polymer science, it serves as a building block for creating functionalized polymers, leading to innovative materials with unique properties for various industrial applications.

Citations