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Catalog Number:
41350
CAS Number:
203866-16-4
Ester méthylique de N -Boc- cis -4-fluoro-L-proline
Purity:
≥ 96,5 % (HPLC)
Synonym(s):
(2 S ,4 S )-1- tert -Butyl-2-méthyl-4-fluoropyrrolidine-1,2-dicarboxylate, Méthyl-(2 S ,4 S ) -N -Boc-4-fluoropyrrolidine-2-carboxylate
Documents
$138.71 /500 mg
Taille
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Informations sur le produit

N-Boc-cis-4-Fluoro-L-proline methyl ester is a valuable compound in the field of medicinal chemistry and pharmaceutical research. This derivative of proline features a tert-butyl carbamate protecting group and a methyl ester, making it an ideal building block for the synthesis of various bioactive molecules. Its unique fluorinated structure enhances its potential as a chiral auxiliary in asymmetric synthesis, allowing researchers to create compounds with specific stereochemical configurations.

This compound is particularly relevant for the development of peptide-based therapeutics and can be utilized in the synthesis of novel inhibitors or modulators in drug discovery processes. Its stability and ease of modification make it a preferred choice for chemists looking to explore new avenues in medicinal applications. Additionally, N-Boc-cis-4-Fluoro-L-proline methyl ester can serve as a key intermediate in the preparation of fluorinated amino acids, which are increasingly important in the design of pharmaceuticals with improved efficacy and reduced side effects.

Numéro CAS 
203866-16-4
Formule moléculaire
C 11 H 18 FNO
Poids moléculaire 
247.26
Indice de réfraction 
n20D = 1,448
Rotation optique 
[α] 20 D = -74 à -60 ° (C = 0,5 dans MeOH)
Informations générales
Numéro CAS 
203866-16-4
Formule moléculaire
C 11 H 18 FNO
Poids moléculaire 
247.26
Indice de réfraction 
n20D = 1,448
Rotation optique 
[α] 20 D = -74 à -60 ° (C = 0,5 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

N-Boc-cis-4-Fluoro-L-proline methyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the creation of peptide-based drugs that target specific biological pathways.
  • Protein Engineering: It is employed in the design of modified peptides and proteins, enhancing their stability and activity, which is vital for drug formulation and therapeutic applications.
  • Research in Neuroscience: The compound is used in studies investigating neuroactive peptides, helping researchers understand their role in neurological disorders and potential treatments.
  • Material Science: Its unique properties make it suitable for developing new materials, including polymers that can be used in drug delivery systems, improving the efficacy of treatments.
  • Biotechnology: This chemical is instrumental in the production of biocatalysts, which are essential for various industrial processes, offering a more sustainable approach compared to traditional chemical methods.

Citations