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Catalog Number:
37981
CAS Number:
155270-99-8
Istradéfylline
Purity:
≥ 98 % (HPLC)
Synonym(s):
( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthyl-1 H -purine-2,6(3 H ,7 H )-dione, ( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthylxanthine
Documents
$146.92 /250 mg
Taille
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Product Information

Istradefylline is a potent selective adenosine A2A receptor antagonist, primarily utilized in the treatment of Parkinson's disease. This compound has shown significant efficacy in enhancing the therapeutic effects of dopaminergic medications, thereby improving motor function and reducing off-time in patients. Its unique mechanism of action allows it to modulate the effects of adenosine, which plays a crucial role in the central nervous system. Researchers and healthcare professionals appreciate Istradefylline for its ability to address motor fluctuations and improve overall quality of life for patients with Parkinson's disease.

In addition to its primary application in neurology, Istradefylline is being explored for potential uses in other neurological disorders, making it a compound of interest for ongoing research. Its favorable pharmacokinetic profile and low incidence of side effects compared to other treatments make it a valuable option for clinicians looking to optimize patient care. With its growing relevance in therapeutic strategies, Istradefylline stands out as a promising agent in the field of neuropharmacology.

Synonyms
( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthyl-1 H -purine-2,6(3 H ,7 H )-dione, ( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthylxanthine
CAS Number
155270-99-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C20H24N4O4
Molecular Weight
384.44
MDL Number
MFCD00928421
PubChem ID
198792
Melting Point
191 - 195 °C
Appearance
Poudre blanche à orange à verte à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthyl-1 H -purine-2,6(3 H ,7 H )-dione, ( E )-8-(3,4-diméthoxystyryl)-1,3-diéthyl-7-méthylxanthine
CAS Number
155270-99-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C20H24N4O4
Molecular Weight
384.44
MDL Number
MFCD00928421
PubChem ID
198792
Melting Point
191 - 195 °C
Appearance
Poudre blanche à orange à verte à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Istradefylline is widely utilized in research focused on:

  • Parkinson's Disease Treatment: It serves as an adjunct therapy for patients experiencing motor fluctuations, enhancing the effectiveness of standard dopaminergic treatments.
  • Neuroprotective Studies: Researchers explore its potential neuroprotective effects, which may help in developing new strategies for neurodegenerative diseases.
  • Pharmacological Research: It is used to study the adenosine A2A receptor's role in various neurological conditions, providing insights into receptor-targeted therapies.
  • Drug Interaction Studies: Istradefylline is valuable in understanding interactions with other medications, helping to optimize treatment regimens for patients.
  • Clinical Trials: It is involved in various clinical trials aimed at assessing its efficacy and safety in different patient populations, contributing to evidence-based medicine.

Citations