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Imatinib
Imatinib is widely utilized in research focused on
- Cancer Treatment: Primarily known for its effectiveness in treating chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs), Imatinib targets specific tyrosine kinases, offering a targeted approach that minimizes damage to healthy cells compared to traditional chemotherapy.
- Research on Drug Resistance: Researchers use Imatinib to study mechanisms of drug resistance in cancer cells, providing insights into how tumors adapt and develop resistance, which can lead to the development of new therapeutic strategies.
- Combination Therapies: Imatinib is often tested in combination with other drugs to enhance treatment efficacy. This application is crucial in oncology, as it may improve outcomes for patients who do not respond to single-agent therapies.
- Pharmacogenomics: The drug is used in studies examining genetic variations that affect patient responses to treatment, helping to personalize cancer therapy based on individual genetic profiles.
- Development of New Inhibitors: Researchers leverage the knowledge gained from Imatinib's mechanism of action to design and develop new inhibitors that target similar pathways, potentially leading to more effective treatments for various cancers.
General Information
Properties
Safety and Regulations
Applications
Imatinib is widely utilized in research focused on
- Cancer Treatment: Primarily known for its effectiveness in treating chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs), Imatinib targets specific tyrosine kinases, offering a targeted approach that minimizes damage to healthy cells compared to traditional chemotherapy.
- Research on Drug Resistance: Researchers use Imatinib to study mechanisms of drug resistance in cancer cells, providing insights into how tumors adapt and develop resistance, which can lead to the development of new therapeutic strategies.
- Combination Therapies: Imatinib is often tested in combination with other drugs to enhance treatment efficacy. This application is crucial in oncology, as it may improve outcomes for patients who do not respond to single-agent therapies.
- Pharmacogenomics: The drug is used in studies examining genetic variations that affect patient responses to treatment, helping to personalize cancer therapy based on individual genetic profiles.
- Development of New Inhibitors: Researchers leverage the knowledge gained from Imatinib's mechanism of action to design and develop new inhibitors that target similar pathways, potentially leading to more effective treatments for various cancers.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
Numéro de catalogue
Numéro de lot/série
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Numéro de catalogue
Numéro de lot/série
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.