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Catalog Number:
37707
CAS Number:
1492-18-8
Folinate de calcium
Purity:
95 - 105 % (dosage, sur une base anhydre)
Synonym(s):
Sel de calcium de l'acide folinique
Documents
$34.85 /1G
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Product Information

Calcium folinate, also known as leucovorin or citrovorum factor, is a vital compound widely utilized in the pharmaceutical industry, particularly in cancer therapy and the treatment of folate deficiency. This active form of folic acid plays a crucial role in enhancing the efficacy of certain chemotherapy agents, such as methotrexate, by mitigating their toxic effects on healthy cells. Its ability to support DNA synthesis and repair makes it an essential adjunct in cancer treatment protocols, helping to reduce side effects and improve patient outcomes. Additionally, calcium folinate is employed in managing conditions related to folate deficiency, such as megaloblastic anemia, providing a rapid and effective means of replenishing folate levels in patients.

The unique properties of calcium folinate, including its high solubility and stability, make it an attractive choice for researchers and healthcare professionals. Its application extends beyond oncology, with potential uses in various fields, including pediatrics and obstetrics, where folate supplementation is critical. By choosing calcium folinate, professionals can ensure optimal therapeutic results while minimizing adverse effects, making it a valuable asset in both clinical and research settings.

Synonyms
Sel de calcium de l'acide folinique
CAS Number
1492-18-8
Purity
95 - 105 % (dosage, sur une base anhydre)
Molecular Formula
C20H21CaN7O7
Molecular Weight
511.51
MDL Number
MFCD00006704
PubChem ID
135408067
Appearance
Poudre cristalline blanche ou jaune clair
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Sel de calcium de l'acide folinique
CAS Number
1492-18-8
Purity
95 - 105 % (dosage, sur une base anhydre)
Molecular Formula
C20H21CaN7O7
Molecular Weight
511.51
MDL Number
MFCD00006704
PubChem ID
135408067
Appearance
Poudre cristalline blanche ou jaune clair
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Calcium folinate is widely utilized in research focused on:

  • Oncology Treatments: It serves as a rescue agent in chemotherapy, particularly for patients receiving methotrexate. By mitigating the drug's toxic effects, it helps improve patient outcomes and reduce side effects.
  • Folic Acid Supplementation: In the medical field, it is used to prevent and treat folate deficiency, especially in pregnant women and individuals with malabsorption issues, ensuring healthy fetal development and overall well-being.
  • Pharmaceutical Formulations: Calcium folinate is incorporated into various drug formulations, enhancing the stability and bioavailability of active ingredients, which is crucial for effective therapeutic outcomes.
  • Research in Biochemistry: It is utilized in laboratory settings to study folate metabolism and its role in cellular processes, providing insights that can lead to new therapeutic strategies.
  • Agricultural Applications: The compound is also explored in agriculture to improve plant growth and nutrient uptake, contributing to sustainable farming practices and increased crop yields.

Citations