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Catalog Number:
37706
CAS Number:
10212-25-6
Chlorhydrate d'ancitabine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Chlorhydrate de 2,2'-anhydro-(1-β-D-arabinofuranosyl)cytosine, Chlorhydrate de 2,2'- O -cyclocytidine
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Product Information

Ancitabine hydrochloride is a potent nucleoside analog with significant applications in the field of oncology. This compound is recognized for its ability to inhibit DNA synthesis, making it a valuable agent in cancer treatment protocols. Its unique structure allows it to interfere with the replication of cancer cells, providing a targeted approach to therapy. Researchers and healthcare professionals utilize Ancitabine hydrochloride in various clinical settings, particularly for hematological malignancies and solid tumors. Its effectiveness in combination therapies enhances its utility, often leading to improved patient outcomes.

In addition to its therapeutic applications, Ancitabine hydrochloride is also a subject of ongoing research, exploring its potential in combination with other chemotherapeutic agents. Its favorable pharmacokinetic profile and ability to penetrate cellular membranes make it a compound of interest for further development in cancer therapeutics. With its established role in treating resistant forms of cancer, Ancitabine hydrochloride stands out as a critical tool for researchers and clinicians aiming to advance cancer treatment strategies.

Synonyms
Chlorhydrate de 2,2'-anhydro-(1-β-D-arabinofuranosyl)cytosine, Chlorhydrate de 2,2'- O -cyclocytidine
CAS Number
10212-25-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C9H11N3O4 · HCl
Molecular Weight
261.66
MDL Number
MFCD00012636
PubChem ID
16757841
Melting Point
264 °C (déc.)
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
[a]20D = -19 à -23 ° (C=2 dans H 2 O)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Chlorhydrate de 2,2'-anhydro-(1-β-D-arabinofuranosyl)cytosine, Chlorhydrate de 2,2'- O -cyclocytidine
CAS Number
10212-25-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C9H11N3O4 · HCl
Molecular Weight
261.66
MDL Number
MFCD00012636
PubChem ID
16757841
Melting Point
264 °C (déc.)
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
[a]20D = -19 à -23 ° (C=2 dans H 2 O)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Ancitabine hydrochloride is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used in oncology as a chemotherapeutic agent. It has shown effectiveness in treating certain types of leukemia, providing patients with a critical option in their treatment regimen.
  • Pharmaceutical Development: Researchers use ancitabine hydrochloride in drug formulation studies to explore its potential in combination therapies, enhancing the efficacy of existing cancer treatments.
  • Cellular Research: It serves as a valuable tool in cellular biology to study the mechanisms of drug resistance in cancer cells, helping scientists understand how to overcome these challenges.
  • Clinical Trials: The compound is often involved in clinical trials aimed at evaluating new treatment protocols, giving researchers insights into its effectiveness and safety in diverse patient populations.
  • Biochemical Studies: Ancitabine hydrochloride is used in various biochemical assays to investigate its interaction with DNA and RNA, contributing to the understanding of nucleic acid metabolism in cancer cells.

Citations