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Catalog Number:
36600
CAS Number:
1028432-04-3
O- ( tert -butyldiméthylsilyl) -N -tosylhydroxylamine
Purity:
≥ 97% (CG)
Synonym(s):
O- ( tert -butyldiméthylsilyl) -N- (toluènesulfonyl)hydroxylamine, O -TBS- N -tosylhydroxylamine
Hazmat
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Product Information

O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is a versatile reagent widely utilized in organic synthesis, particularly in the field of medicinal chemistry. This compound serves as an effective protecting group for amines, allowing for selective reactions without interfering with other functional groups. Its unique structure, featuring a tert-butyldimethylsilyl group, enhances stability and solubility, making it an ideal choice for complex synthetic pathways. Researchers appreciate its utility in the synthesis of various pharmaceuticals and agrochemicals, where precision and efficiency are paramount.

In addition to its role in protecting amines, O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is also employed in the development of novel compounds through its ability to facilitate the formation of nitrogen-containing heterocycles. This capability opens avenues for the creation of new therapeutic agents, particularly in the fight against resistant pathogens. With its favorable properties and broad applicability, this compound stands out as a valuable tool for chemists aiming to innovate and streamline their synthetic processes.

Synonyms
O- ( tert -butyldiméthylsilyl) -N- (toluènesulfonyl)hydroxylamine, O -TBS- N -tosylhydroxylamine
CAS Number
1028432-04-3
Purity
≥ 97% (CG)
Molecular Formula
C 13 H 23 NO 3 SSi
Molecular Weight
301.48
MDL Number
MFCD11976059
PubChem ID
24899640
Melting Point
90 - 96 °C
Appearance
Poudre blanche à blanc cassé à beige
Conditions
Conserver à température ambiante, sous gaz inerte
General Information
Synonyms
O- ( tert -butyldiméthylsilyl) -N- (toluènesulfonyl)hydroxylamine, O -TBS- N -tosylhydroxylamine
CAS Number
1028432-04-3
Purity
≥ 97% (CG)
Molecular Formula
C 13 H 23 NO 3 SSi
Molecular Weight
301.48
MDL Number
MFCD11976059
PubChem ID
24899640
Melting Point
90 - 96 °C
Appearance
Poudre blanche à blanc cassé à beige
Conditions
Conserver à température ambiante, sous gaz inerte
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

O-(tert-Butyldimethylsilyl)-N-tosylhydroxylamine is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, particularly in the synthesis of amines and other nitrogen-containing compounds. Its ability to protect hydroxyl groups enhances reaction efficiency.
  • Drug Development: In pharmaceutical research, it is used to modify drug candidates, improving their stability and bioavailability. This is crucial for developing effective medications with fewer side effects.
  • Analytical Chemistry: The compound is employed in sample preparation techniques, aiding in the analysis of complex mixtures. Its properties help in isolating specific compounds for accurate testing.
  • Material Science: It finds applications in the development of advanced materials, particularly in creating functionalized polymers that exhibit enhanced properties for various industrial uses.
  • Bioconjugation: This chemical is used in bioconjugation processes, linking biomolecules for research in biotechnology and diagnostics, which is essential for developing targeted therapies and diagnostic tools.

Citations