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Catalog Number:
36412
CAS Number:
503-38-8
Chloroformiate de trichlorométhyle
Purity:
≥ 97% (CG)
Synonym(s):
Diphosgène, TCF
Hazmat
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$156.00 /10ML
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Product Information

Trichloromethyl chloroformate is a versatile reagent widely utilized in organic synthesis, particularly in the production of various pharmaceuticals and agrochemicals. This compound serves as an effective acylating agent, facilitating the introduction of acyl groups into organic molecules, which is crucial for the development of complex chemical structures. Its unique reactivity allows for the formation of esters and amides, making it an essential tool in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. Researchers appreciate its efficiency in reactions that require chlorination, as it can enhance yields and reduce reaction times compared to alternative methods.

In addition to its applications in the pharmaceutical industry, trichloromethyl chloroformate is also employed in the preparation of various intermediates and specialty chemicals. Its ability to selectively react with nucleophiles makes it invaluable in the development of new materials and compounds. With its high reactivity and specificity, this compound stands out as a preferred choice for chemists looking to streamline their synthetic processes while achieving high purity and efficiency in their products.

Synonyms
Diphosgène, TCF
CAS Number
503-38-8
Purity
≥ 97% (CG)
Molecular Formula
ClCOOCCl3
Molecular Weight
197.83
MDL Number
MFCD00015553
PubChem ID
10426
Density
1.639
Appearance
Liquide incolore
Boiling Point
20 ?C/10 mmHg
Refractive Index
1.458
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Diphosgène, TCF
CAS Number
503-38-8
Purity
≥ 97% (CG)
Molecular Formula
ClCOOCCl3
Molecular Weight
197.83
MDL Number
MFCD00015553
PubChem ID
10426
Density
1.639
Appearance
Liquide incolore
Boiling Point
20 ?C/10 mmHg
Refractive Index
1.458
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Trichloromethyl chloroformate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, allowing researchers to create complex molecules efficiently.
  • Protecting Group Chemistry: It is commonly used to introduce trichloromethyl groups in organic synthesis, which can later be removed, making it valuable for protecting functional groups during multi-step reactions.
  • Polymer Chemistry: In the production of specialty polymers, this chemical acts as a chlorinating agent, enhancing the properties of the final product, such as thermal stability and chemical resistance.
  • Analytical Chemistry: Trichloromethyl chloroformate is employed in derivatization processes for the analysis of alcohols and amines, improving detection sensitivity in techniques like gas chromatography.
  • Pharmaceutical Development: It plays a critical role in the synthesis of active pharmaceutical ingredients (APIs), streamlining the development of new medications by facilitating complex chemical transformations.

Citations