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Catalog Number:
33408
Fmoc-L-Aph(D-Hor)-OH
Purity:
≥ 96 % (HPLC)
Synonym(s):
Acide (S)-2-((((Fmoc)amino)-3-(4-((R)-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
Documents
$79.22 /100 mg
Taille
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Product Information

Fmoc-L-Aph(D-Hor)-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the incorporation of D-hydroxyphenylalanine (D-Hor), enhancing the stability and bioactivity of the resulting peptides. Researchers often leverage this compound in the development of novel therapeutics, particularly in the fields of oncology and neurobiology, where modified peptides can exhibit improved efficacy and specificity.

The versatility of Fmoc-L-Aph(D-Hor)-OH extends to its application in solid-phase peptide synthesis (SPPS), where it facilitates the efficient assembly of complex peptide chains. Its ability to provide high yields and purity makes it an attractive choice for both academic and industrial laboratories. Additionally, this compound can be used in the design of peptide-based drugs, offering potential advantages over traditional small-molecule drugs, such as enhanced selectivity and reduced side effects. With its robust performance in peptide synthesis and therapeutic applications, Fmoc-L-Aph(D-Hor)-OH stands out as a valuable tool for researchers and industry professionals alike.

Synonyms
Acide (S)-2-((((Fmoc)amino)-3-(4-((R)-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
Purity
≥ 96 % (HPLC)
Molecular Formula
C29H26N4O7
Molecular Weight
542.4
Appearance
Poudre blanche à blanc cassé
Conditions
Magasin chez RT
General Information
Synonyms
Acide (S)-2-((((Fmoc)amino)-3-(4-((R)-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
Purity
≥ 96 % (HPLC)
Molecular Formula
C29H26N4O7
Molecular Weight
542.4
Appearance
Poudre blanche à blanc cassé
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-Aph(D-Hor)-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids while maintaining the integrity of the peptide chain.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, particularly in targeting specific biological pathways, thus enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes, facilitating the attachment of peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for the development of novel neuropeptides that can modulate neural activity, providing insights into brain function.
  • Analytical Chemistry: Fmoc-L-Aph(D-Hor)-OH is employed in analytical methods for characterizing peptide structures, aiding researchers in understanding peptide behavior and interactions.

Citations