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Catalog Number:
33336
CAS Number:
1253282-31-3
Fmoc-L-Aph(L-Hor)-OH
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide ( S )-2-((((Fmoc)amino)-3-(4-(( S )-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
Documents
$55.00 /100 mg
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Product Information

Fmoc-L-Aph(L-Hor)-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, which includes a 1,3-diazinane moiety, enhances its stability and reactivity, making it an ideal choice for researchers looking to develop complex peptide sequences.

In practical applications, Fmoc-L-Aph(L-Hor)-OH is particularly valuable in the pharmaceutical industry for the synthesis of bioactive peptides, which can serve as therapeutic agents or research tools. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the efficient assembly of peptides with diverse biological activities. Researchers benefit from its high purity and reliability, ensuring consistent results in their experiments. This compound stands out among similar products due to its robust performance in challenging synthetic environments, making it a preferred choice for professionals in medicinal chemistry and biochemistry.

Synonyms
Acide ( S )-2-((((Fmoc)amino)-3-(4-(( S )-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
CAS Number
1253282-31-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C26H26N4O7
Molecular Weight
542.4
MDL Number
MFCD27923015
PubChem ID
78158190
Appearance
Poudre blanc cassé
Optical Rotation
[a] D 20 = 17 ± 2 ° (C = 2 dans DMF)
Conditions
Magasin chez RT
General Information
Synonyms
Acide ( S )-2-((((Fmoc)amino)-3-(4-(( S )-2,6-dioxohexahydropyrimidine-4-carboxamido)phényl)propanoïque
CAS Number
1253282-31-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C26H26N4O7
Molecular Weight
542.4
MDL Number
MFCD27923015
PubChem ID
78158190
Appearance
Poudre blanc cassé
Optical Rotation
[a] D 20 = 17 ± 2 ° (C = 2 dans DMF)
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-Aph(L-Hor)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective assembly of complex peptides while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in oncology and infectious diseases, by enhancing the stability and bioavailability of peptide drugs.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems and diagnostic agents.
  • Research in Neuroscience: It is applied in the synthesis of neuropeptides, contributing to the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Custom Peptide Libraries: Researchers utilize this compound to create diverse peptide libraries for high-throughput screening, aiding in the discovery of new bioactive compounds.

Citations