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Catalog Number:
32764
CAS Number:
184901-82-4, 102129-66-8
H-Ala-Ala-Phe-chlorométhylcétone·TFA
Synonym(s):
AAF-CMK·TFA
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Product Information

H-Ala-Ala-Phe-chloromethylketone·TFA is a potent peptide derivative that plays a significant role in biochemical research and pharmaceutical development. This compound, known for its unique structure, features a chloromethylketone moiety that enhances its reactivity, making it an invaluable tool for peptide synthesis and modification. Its ability to selectively inhibit proteolytic enzymes positions it as a critical component in the study of enzyme kinetics and protein interactions. Researchers utilize H-Ala-Ala-Phe-chloromethylketone·TFA in various applications, including drug design, where it serves as a building block for more complex peptide structures, and in the development of therapeutic agents targeting specific biological pathways.

The trifluoroacetic acid (TFA) component of this compound not only aids in solubility but also stabilizes the peptide during synthesis, ensuring high yields and purity. This makes H-Ala-Ala-Phe-chloromethylketone·TFA particularly advantageous for laboratories focused on high-throughput screening and peptide library generation. Its unique properties and versatility make it an essential reagent for researchers aiming to explore new therapeutic avenues and enhance their understanding of peptide biology.

Synonyms
AAF-CMK·TFA
CAS Number
184901-82-4, 102129-66-8
Molecular Formula
C16H22ClN3O3 · C2HF3O2
Molecular Weight
453.85
MDL Number
MFCD01310850
PubChem ID
16760685
Conditions
Conserver à ≤ -10 °C
General Information
Synonyms
AAF-CMK·TFA
CAS Number
184901-82-4, 102129-66-8
Molecular Formula
C16H22ClN3O3 · C2HF3O2
Molecular Weight
453.85
MDL Number
MFCD01310850
PubChem ID
16760685
Conditions
Conserver à ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

H-Ala-Ala-Phe-chloromethylketone·TFA is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable reagent in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its ability to selectively modify amino acids enhances the efficiency of creating complex peptide structures.
  • Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. The compound's unique properties allow for the design of inhibitors that can target specific biological pathways, making it essential for developing new therapeutic agents.
  • Biochemical Research: Researchers employ this chemical in studies related to enzyme inhibition and protein interactions. Its role in modulating biological activity aids in understanding disease mechanisms and potential treatment strategies.
  • Diagnostics: The compound can be utilized in the development of diagnostic tools, particularly in assays that require specific peptide interactions. Its precision in binding can enhance the sensitivity and specificity of diagnostic tests.
  • Material Science: In the field of materials, it can be used to create peptide-based materials with unique properties. These materials can be applied in drug delivery systems, offering advantages in targeted therapy and controlled release.

Citations