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Catalog Number:
22117
CAS Number:
24729-96-2
Clindamycine 2-phosphate
Grade:
répond aux spécifications USP
Purity:
≥ 780 µg/mg (dosage, base anhydre)
Synonym(s):
Phosphate de clindamycine 2-dihydrogène
Antibiotic
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Product Information

Clindamycin 2-phosphate is a potent prodrug of clindamycin, a lincosamide antibiotic renowned for its effectiveness against a variety of Gram-positive bacteria and anaerobic infections. This compound is particularly valuable in the pharmaceutical industry, where it is utilized in the formulation of topical and systemic treatments for bacterial infections, including skin and soft tissue infections. Its unique phosphate ester structure enhances its solubility and stability, making it an ideal candidate for drug delivery systems.

In research settings, Clindamycin 2-phosphate serves as a critical tool for studying bacterial resistance mechanisms and the pharmacokinetics of lincosamide antibiotics. Its ability to penetrate bacterial membranes allows for effective intracellular action, providing a significant advantage over other antibiotics that may struggle with similar penetration. This compound's versatility and efficacy make it a preferred choice for both clinical applications and laboratory studies, ensuring reliable results in combating resistant bacterial strains.

Synonyms
Phosphate de clindamycine 2-dihydrogène
CAS Number
24729-96-2
Purity
≥ 780 µg/mg (dosage, base anhydre)
Grade
répond aux spécifications USP
Molecular Formula
C18H34ClN2O8PS
Molecular Weight
504.96
MDL Number
MFCD11982855
PubChem ID
32603
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Phosphate de clindamycine 2-dihydrogène
CAS Number
24729-96-2
Purity
≥ 780 µg/mg (dosage, base anhydre)
Grade
répond aux spécifications USP
Molecular Formula
C18H34ClN2O8PS
Molecular Weight
504.96
MDL Number
MFCD11982855
PubChem ID
32603
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Oui
DEA-regulated
Non
Warnings
-
Applications

Clindamycin 2-phosphate is widely utilized in research focused on:

  • Antibiotic Development: This compound serves as a prodrug for clindamycin, which is effective against various bacterial infections. Researchers use it to develop new formulations that enhance its stability and efficacy.
  • Topical Treatments: In dermatology, it is incorporated into topical formulations for treating acne and skin infections, providing targeted action with minimal systemic absorption.
  • Pharmaceutical Research: Clindamycin 2-phosphate is studied for its pharmacokinetics and pharmacodynamics, aiding in the design of more effective antibiotic therapies.
  • Veterinary Medicine: It is applied in veterinary formulations to treat infections in animals, showcasing its versatility beyond human medicine.
  • Combination Therapies: The compound is often used in combination with other antibiotics to enhance therapeutic outcomes and combat antibiotic resistance, making it a valuable tool in modern medicine.

Citations