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Catalog Number:
07424
CAS Number:
220497-98-3
Fmoc-D-propraglycine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-propragyl-Gly-OH, Fmoc-D-Pra-OH, ( Acide R -2-(Fmoc-amino)-4-pentynoïque
Documents
$79.22 /250 mg
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Product Information

Fmoc-D-propraglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it a preferred choice among researchers and industry professionals engaged in the development of complex peptide-based therapeutics. Fmoc-D-propraglycine is particularly valuable in the synthesis of bioactive peptides and can be employed in various applications, including the design of inhibitors, vaccines, and other pharmaceutical agents.

The compound's stability and compatibility with standard coupling reagents enhance its utility in solid-phase peptide synthesis (SPPS), enabling the production of high-purity peptides with minimal side reactions. Researchers appreciate its ability to facilitate the introduction of non-standard amino acids into peptide sequences, expanding the scope of peptide libraries for drug discovery. With its proven track record in advancing peptide chemistry, Fmoc-D-propraglycine stands out as a crucial building block for innovative therapeutic solutions.

Synonyms
Fmoc-D-propragyl-Gly-OH, Fmoc-D-Pra-OH, ( Acide R -2-(Fmoc-amino)-4-pentynoïque
CAS Number
220497-98-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 174
Molecular Weight
335.3
MDL Number
MFCD01311781
PubChem ID
4418905
Melting Point
171-177 ?C
Optical Rotation
[a] D 20 = +19 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-D-propragyl-Gly-OH, Fmoc-D-Pra-OH, ( Acide R -2-(Fmoc-amino)-4-pentynoïque
CAS Number
220497-98-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 174
Molecular Weight
335.3
MDL Number
MFCD01311781
PubChem ID
4418905
Melting Point
171-177 ?C
Optical Rotation
[a] D 20 = +19 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-D-propraglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting the overall structure.
  • Drug Development: It plays a crucial role in the development of new pharmaceuticals, particularly in creating compounds with enhanced bioactivity and stability.
  • Bioconjugation: Fmoc-D-propraglycine is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutics.
  • Research in Neuroscience: This compound is valuable in studying neuropeptides, contributing to our understanding of brain functions and potential treatments for neurological disorders.
  • Custom Synthesis Services: Many research labs utilize it for custom synthesis projects, benefiting from its versatility and effectiveness in producing specific peptide sequences.

Citations