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Catalog Number:
04084
CAS Number:
199110-64-0
Fmoc- p -phényl-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Bip(4,4')-OH, Fmoc-L-Ala(4,4'-biphényl)-OH, Fmoc-Bip(4,4')-OH
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Product Information

Fmoc-p-phenyl-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amine functionalities during the synthesis of peptides. Its unique structure, characterized by the presence of a phenyl group, enhances the stability and solubility of peptides, making it an ideal choice for researchers and professionals in the pharmaceutical and biotechnology industries.

In practical applications, Fmoc-p-phenyl-L-phenylalanine is commonly employed in solid-phase peptide synthesis (SPPS), facilitating the efficient assembly of complex peptides and proteins. Its ability to improve the yield and purity of synthesized compounds makes it a valuable tool for researchers working on therapeutic peptides, including those targeting cancer and other diseases. Additionally, the compound's compatibility with various coupling reagents and its ease of removal under mild conditions further enhance its appeal in synthetic chemistry, allowing for streamlined workflows and reduced reaction times.

Synonyms
Fmoc-L-Bip(4,4')-OH, Fmoc-L-Ala(4,4'-biphényl)-OH, Fmoc-Bip(4,4')-OH
CAS Number
199110-64-0
Purity
≥ 98 % (HPLC)
Molecular Formula
C 30 H 254
Molecular Weight
463.52
MDL Number
MFCD00191198
PubChem ID
18450295
Melting Point
182 - 187 °C (lit.)
Appearance
Poudre blanche à jaune pâle
Optical Rotation
[a] D 20 = -12 ± 2 ° (C = 1 dans DMF) (Lit.)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Bip(4,4')-OH, Fmoc-L-Ala(4,4'-biphényl)-OH, Fmoc-Bip(4,4')-OH
CAS Number
199110-64-0
Purity
≥ 98 % (HPLC)
Molecular Formula
C 30 H 254
Molecular Weight
463.52
MDL Number
MFCD00191198
PubChem ID
18450295
Melting Point
182 - 187 °C (lit.)
Appearance
Poudre blanche à jaune pâle
Optical Rotation
[a] D 20 = -12 ± 2 ° (C = 1 dans DMF) (Lit.)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-p-phenyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptides with high purity and yield.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, offering a way to modify peptide structures for enhanced bioactivity and stability.
  • Bioconjugation: Used in bioconjugation techniques, it helps in attaching peptides to various biomolecules, facilitating the development of targeted therapies and diagnostic agents.
  • Research in Protein Engineering: This compound aids researchers in protein engineering by enabling the incorporation of non-natural amino acids into proteins, which can enhance their properties for specific applications.
  • Fluorescent Labeling: It can be utilized for fluorescent labeling of peptides, making it valuable in imaging and tracking biological processes in live cells or tissues.

Citations