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Catalog Number:
02653
CAS Number:
77128-70-2
Fmoc-sarcosine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-Sar-OH, Fmoc- N -méthylglycine
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Product Information

Fmoc-sarcosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for easy cleavage of the Fmoc group under mild conditions, making it an ideal choice for researchers looking to streamline their synthesis processes. Fmoc-sarcosine is particularly valuable in the production of peptide-based therapeutics, where precision and efficiency are paramount.

In addition to its applications in peptide synthesis, Fmoc-sarcosine has shown promise in the development of novel drug candidates and in the study of biological processes involving amino acids. Its compatibility with various coupling reagents and solid-phase synthesis techniques enhances its utility in both academic and industrial settings. Researchers and professionals in the pharmaceutical and biotechnology sectors can leverage Fmoc-sarcosine to create high-purity peptides, facilitating advancements in drug discovery and development.

Synonyms
Fmoc-Sar-OH, Fmoc- N -méthylglycine
CAS Number
77128-70-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C 18 H 17 NON 4
Molecular Weight
311.3
MDL Number
MFCD00151926
PubChem ID
688640
Melting Point
95 - 120 ?C
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-Sar-OH, Fmoc- N -méthylglycine
CAS Number
77128-70-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C 18 H 17 NON 4
Molecular Weight
311.3
MDL Number
MFCD00151926
PubChem ID
688640
Melting Point
95 - 120 ?C
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-sarcosine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its role in modifying peptide structures makes it valuable in the pharmaceutical industry for developing new therapeutic agents, particularly in oncology and immunology.
  • Bioconjugation: Fmoc-sarcosine can be used to attach biomolecules to surfaces or other compounds, enhancing drug delivery systems and diagnostic tools.
  • Research in Neuroscience: It is often employed in studies related to neuropeptides, helping scientists understand neuronal signaling and potential treatments for neurological disorders.
  • Custom Peptide Libraries: The compound facilitates the creation of diverse peptide libraries for screening and identifying novel biological activities, which is crucial in drug discovery.

Citations