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Catalog Number:
02651
CAS Number:
138774-92-2
Fmoc- N -méthyl-D-alanine
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-N-Me-D-Ala-OH
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Product Information

Fmoc-N-methyl-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focused on developing complex peptide sequences. The N-methyl substitution enhances the compound's stability and solubility, which is particularly beneficial in various organic synthesis applications.

In the pharmaceutical industry, Fmoc-N-methyl-D-alanine is employed in the design of peptide-based therapeutics, including those targeting neurological disorders and cancer. Its ability to facilitate the synthesis of modified peptides opens avenues for creating novel drug candidates with improved efficacy and reduced side effects. Researchers appreciate its compatibility with automated synthesizers, streamlining the peptide synthesis process. With its robust performance and adaptability, Fmoc-N-methyl-D-alanine stands out as a crucial building block for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-N-Me-D-Ala-OH
CAS Number
138774-92-2
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 19 H 194
Molecular Weight
325.3
MDL Number
MFCD00153385
PubChem ID
3912665
Melting Point
~ 155 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 20 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-N-Me-D-Ala-OH
CAS Number
138774-92-2
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 19 H 194
Molecular Weight
325.3
MDL Number
MFCD00153385
PubChem ID
3912665
Melting Point
~ 155 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 20 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-N-methyl-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studies in biochemistry and pharmacology.
  • Drug Development: Its unique properties make it valuable in the development of new drugs, particularly in designing molecules that can interact effectively with biological targets.
  • Protein Engineering: Used in the modification of proteins, it helps scientists enhance the stability and functionality of proteins for various applications in biotechnology.
  • Research in Neuroscience: This compound is instrumental in studying neurotransmitter systems, providing insights into neurological functions and potential therapeutic targets.
  • Bioconjugation: Fmoc-N-methyl-D-alanine is utilized in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial for diagnostics and therapeutic applications.

Citations