Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02454
CAS Number:
71989-33-8
Fmoc- O - tert -butyl-L-sérine
Purity:
≥ 99,5 % (HPLC chirale, HPLC)
Synonym(s):
Fmoc-L-Ser(tBu)-OH
Documents
$25.00 /5G
Taille
Request Bulk Quote
Product Information

Fmoc-O-tert-butyl-L-serine is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the field of medicinal chemistry and drug development. Its tert-butyl group enhances solubility and stability, facilitating smoother reactions and improving yields in complex synthetic pathways.

Researchers and industry professionals appreciate Fmoc-O-tert-butyl-L-serine for its role in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. This compound is particularly advantageous in solid-phase peptide synthesis (SPPS), where its protective groups can be easily removed under mild conditions, allowing for the efficient assembly of peptides. Its unique properties make it a preferred choice for those looking to streamline their synthesis processes while achieving high purity and functionality in their final products.

Synonyms
Fmoc-L-Ser(tBu)-OH
CAS Number
71989-33-8
Purity
≥ 99,5 % (HPLC chirale, HPLC)
Molecular Formula
C 22 H 255
Molecular Weight
383.4
MDL Number
MFCD00037127
PubChem ID
3085671
Melting Point
125 - 140 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 25 ± 3 º (C = 1 dans EtOAc)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Ser(tBu)-OH
CAS Number
71989-33-8
Purity
≥ 99,5 % (HPLC chirale, HPLC)
Molecular Formula
C 22 H 255
Molecular Weight
383.4
MDL Number
MFCD00037127
PubChem ID
3085671
Melting Point
125 - 140 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = 25 ± 3 º (C = 1 dans EtOAc)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-O-tert-butyl-L-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for the amino acid serine during peptide synthesis, allowing for the selective modification of other amino acids without affecting serine.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in the development of drugs targeting specific biological pathways.
  • Bioconjugation: Researchers use it to facilitate the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics.
  • Protein Engineering: The compound is used in the modification of proteins to improve their stability and functionality, which is essential in various biotechnological applications.
  • Research in Neuroscience: It is applied in studies involving neurotransmitter systems, where modified peptides can help in understanding receptor interactions and signaling pathways.

Citations