Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02448
CAS Number:
71989-31-6
Fmoc-L-proline
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Pro-OH, ( Acide S -Fmoc-pyrrolidine-2-carboxylique
Documents
$18.53 /5G
Taille
Request Bulk Quote
Product Information

La Fmoc-L-Proline est utilisée dans la synthèse de peptides pour introduire la proline, un acide aminé connu pour induire des virages dans les chaînes peptidiques et affecter la conformation globale des peptides et des protéines. Le groupe protecteur Fmoc permet l'ajout séquentiel d'acides aminés, la proline jouant un rôle central dans les relations structure-activité des peptides bioactifs, notamment les peptides de signalisation, les inhibiteurs d'enzymes et les peptides antimicrobiens.

Synonyms
Fmoc-L-Pro-OH, ( Acide S -Fmoc-pyrrolidine-2-carboxylique
CAS Number
71989-31-6
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 20 H 194
Molecular Weight
337.4
MDL Number
MFCD00037122
PubChem ID
100106
Melting Point
100 - 118 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -32 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Pro-OH, ( Acide S -Fmoc-pyrrolidine-2-carboxylique
CAS Number
71989-31-6
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 20 H 194
Molecular Weight
337.4
MDL Number
MFCD00037122
PubChem ID
100106
Melting Point
100 - 118 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -32 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective formation of peptide bonds while preventing unwanted reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, Fmoc-L-proline is used to create peptide-based drugs. Its ability to enhance the stability and bioavailability of therapeutic peptides is crucial in developing effective medications.
  • Bioconjugation: The compound is employed in bioconjugation processes to attach biomolecules to surfaces or other molecules. This application is vital in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers utilize Fmoc-L-proline in the design of modified proteins. Its unique structure allows for the incorporation of proline residues, which can influence protein folding and stability, leading to improved functionality.
  • Material Science: In the development of new materials, Fmoc-L-proline is used to create polymeric systems with specific properties. Its role in enhancing the mechanical and thermal properties of materials is beneficial in various industrial applications.

Citations