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Catalog Number:
02415
CAS Number:
84793-07-7
Ester α- tert -butylique de l'acide Fmoc-L-glutamique
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Glu-OtBu
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Product Information

Fmoc-L-glutamic acid a-tert-butyl ester is a versatile and valuable compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of L-glutamic acid features a fluorenylmethoxycarbonyl (Fmoc) group, which provides excellent stability during synthetic processes while allowing for easy deprotection when needed. Its unique structure enhances solubility and reactivity, making it an ideal choice for researchers looking to develop complex peptides and proteins.

In the field of medicinal chemistry, Fmoc-L-glutamic acid a-tert-butyl ester serves as a crucial building block for the synthesis of bioactive peptides, which can be employed in drug development and therapeutic applications. Its ability to facilitate the introduction of functional groups while maintaining the integrity of the amino acid backbone is particularly advantageous in the design of peptide-based drugs. Researchers appreciate its reliable performance in solid-phase peptide synthesis, contributing to the efficient production of high-purity peptides for various applications, including targeted therapies and diagnostics.

Synonyms
Fmoc-L-Glu-OtBu
CAS Number
84793-07-7
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 24 H 276
Molecular Weight
425.5
MDL Number
MFCD00065648
Melting Point
100 - 112 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -11 ± 1,5 º (C = 1 dans AcOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Glu-OtBu
CAS Number
84793-07-7
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 24 H 276
Molecular Weight
425.5
MDL Number
MFCD00065648
Melting Point
100 - 112 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -11 ± 1,5 º (C = 1 dans AcOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-glutamic acid a-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides in pharmaceuticals.
  • Drug Development: It plays a significant role in the development of new drugs, particularly in designing compounds that target specific biological pathways, enhancing the efficacy of therapeutic agents.
  • Biotechnology: In the field of biotechnology, it is used to create modified proteins that can improve the stability and activity of enzymes, which are essential for various industrial processes.
  • Research in Neuroscience: The compound is utilized in studies related to neurotransmitter pathways, particularly in understanding the role of glutamic acid in synaptic transmission, which is vital for developing treatments for neurological disorders.
  • Analytical Chemistry: It is employed in analytical methods to separate and identify amino acids and peptides, providing researchers with valuable data for quality control in pharmaceutical manufacturing.

Citations