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Catalog Number:
00145
CAS Number:
35661-60-0
Fmoc-L-leucine
Purity:
≥ 99,7 % (HPLC chirale)
Synonym(s):
Fmoc-L-Leu-OH
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Product Information

Forme protégée de l'acide aminé leucine utilisée dans la synthèse des peptides, permettant une incorporation sélective dans les chaînes peptidiques. Elle joue un rôle dans la recherche sur les maladies métaboliques en tant que modulateur sélectif du PPARα, et s'avère prometteuse pour améliorer la sensibilité à l'insuline avec une activité adipogénique plus faible.

Synonyms
Fmoc-L-Leu-OH
CAS Number
35661-60-0
Purity
≥ 99,7 % (HPLC chirale)
Molecular Formula
C 21 H 234
Molecular Weight
353.4
MDL Number
MFCD00037133
PubChem ID
4308
Melting Point
148 - 163 ?C
Appearance
Poudre blanche ou cristaux blancs à blanc cassé
Optical Rotation
[a] D 20 = -25 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Leu-OH
CAS Number
35661-60-0
Purity
≥ 99,7 % (HPLC chirale)
Molecular Formula
C 21 H 234
Molecular Weight
353.4
MDL Number
MFCD00037133
PubChem ID
4308
Melting Point
148 - 163 ?C
Appearance
Poudre blanche ou cristaux blancs à blanc cassé
Optical Rotation
[a] D 20 = -25 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-leucine is widely utilized in research focused on:

  • Peptide Synthesis: This chemical serves as a key building block in the synthesis of peptides, allowing researchers to create complex protein structures for various studies.
  • Drug Development: Its role in medicinal chemistry is significant, as it helps in designing and optimizing peptide-based drugs, particularly in targeting specific biological pathways.
  • Biotechnology: In the field of biotechnology, it is used to produce recombinant proteins, enhancing the efficiency of protein expression systems.
  • Research in Neuroscience: Fmoc-L-leucine is employed in studies related to neurotransmitter functions, aiding in the understanding of neurological disorders.
  • Material Science: This compound is also explored in the development of biomaterials, particularly in creating hydrogels for drug delivery applications.

Citations