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Catalog Number:
02413
CAS Number:
204251-24-1, 71989-18-9
Fmoc-L-glutamic acid γ-tert-butyl ester hydrate
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
Fmoc-L-Glu(OtBu)-OH hydrate, Fmoc-L-glutamic acid 5-tert-butyl ester hydrate
Documents
$20.20 /5G
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Product Information

Fmoc-L-glutamic acid g-tert-butyl ester hydrate is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its tert-butyl ester functionality enhances solubility and stability, making it an ideal choice for various organic synthesis applications. Researchers appreciate its role in facilitating the formation of complex peptides, which are crucial in drug development and biochemistry.

In addition to its applications in peptide synthesis, Fmoc-L-glutamic acid g-tert-butyl ester hydrate is also valuable in the study of protein interactions and enzyme activity. Its unique structure allows for the exploration of glutamic acid's role in biological systems, providing insights into metabolic pathways and potential therapeutic targets. This compound stands out for its ease of use and effectiveness in producing high-purity peptides, making it a preferred choice among professionals in the fields of medicinal chemistry and biochemistry.

Synonyms
Fmoc-L-Glu(OtBu)-OH hydrate, Fmoc-L-glutamic acid 5-tert-butyl ester hydrate
CAS Number
204251-24-1, 71989-18-9
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C24H27NO6·H2O
Molecular Weight
443.49
MDL Number
MFCD00150485
PubChem ID
7009548
Melting Point
80 - 100 °C
Appearance
White powder
Optical Rotation
[a]D20 = -8.5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Glu(OtBu)-OH hydrate, Fmoc-L-glutamic acid 5-tert-butyl ester hydrate
CAS Number
204251-24-1, 71989-18-9
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C24H27NO6·H2O
Molecular Weight
443.49
MDL Number
MFCD00150485
PubChem ID
7009548
Melting Point
80 - 100 °C
Appearance
White powder
Optical Rotation
[a]D20 = -8.5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g-tert-butyl ester hydrate is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in creating compounds that target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in developing biosensors and drug delivery systems.
  • Research in Neuroscience: Its derivatives are often employed in studies related to neurotransmitter signaling, helping researchers explore the role of glutamate in brain function and disorders.
  • Material Science: The compound is also explored in the development of new materials, particularly in creating polymers that require specific functional groups for enhanced properties.

Citations