Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
12773
CAS Number:
203854-49-3
Fmoc-L-β-homoglutamic acid 6-tert-butyl ester
Purity:
≥ 95%
Synonym(s):
Fmoc-L-β-HomoGlu(OtBu)-OH, (S-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
Documents
$141.41 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-b-homoglutamic acid 6-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for improved solubility and stability, making it an excellent choice for researchers working on complex peptide sequences. The tert-butyl ester further enhances its utility by providing a stable and easily removable protecting group, facilitating the synthesis of various bioactive compounds.

In addition to its applications in peptide synthesis, Fmoc-L-b-homoglutamic acid 6-tert-butyl ester is also valuable in the development of pharmaceuticals and bioconjugates. Its ability to form stable linkages with other biomolecules opens up possibilities for creating targeted drug delivery systems and therapeutic agents. Researchers in medicinal chemistry and biochemistry will find this compound particularly beneficial for its efficiency in streamlining synthesis processes while maintaining high yields and purity.

Synonyms
Fmoc-L-β-HomoGlu(OtBu)-OH, (S-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
CAS Number
203854-49-3
Purity
≥ 95%
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD01863053
PubChem ID
4283598
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -11 ± 2.5º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-β-HomoGlu(OtBu)-OH, (S-3-(Fmoc-amino)adipic acid 6-tert-butyl ester
CAS Number
203854-49-3
Purity
≥ 95%
Molecular Formula
C25H29NO6
Molecular Weight
439.51
MDL Number
MFCD01863053
PubChem ID
4283598
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -11 ± 2.5º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-homoglutamic acid 6-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a role in the design of peptide-based therapeutics, particularly in enhancing the stability and bioavailability of drug candidates.
  • Bioconjugation: The compound is used in bioconjugation processes, aiding in the attachment of peptides to various biomolecules, which is essential for developing targeted drug delivery systems.
  • Research in Neuroscience: It is involved in studies related to neurotransmitter systems, particularly in understanding the role of glutamate in synaptic transmission and neuroprotection.
  • Material Science: The compound can be incorporated into polymeric materials, enhancing their properties for applications in drug delivery systems and tissue engineering.

Citations