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Catalog Number:
16809
CAS Number:
1217728-65-8
Fmoc-L-2,4-dimethylphenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Phe(2,4-DiCH3)-OH, (S)-Fmoc-2-amino-3-(2,4-dimethylphenyl)propionic acid, Fmoc-Phe(2,4-DiCH3)-OH
Documents
$80.50 /250MG
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Product Information

Fmoc-L-2,4-dimethylphenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, characterized by its fluorenylmethoxycarbonyl (Fmoc) protecting group, offers enhanced stability and solubility, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure allows for the introduction of bulky side chains, which can significantly influence the biological activity and specificity of peptides.

In practical applications, Fmoc-L-2,4-dimethylphenylalanine is particularly valuable in the synthesis of peptide libraries for high-throughput screening, enabling the discovery of novel therapeutic agents. Additionally, its role in solid-phase peptide synthesis (SPPS) facilitates the efficient assembly of complex peptides, streamlining the research process. Researchers appreciate its compatibility with various coupling reagents and its ability to enhance the overall yield of peptide synthesis, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-L-Phe(2,4-DiCH3)-OH, (S)-Fmoc-2-amino-3-(2,4-dimethylphenyl)propionic acid, Fmoc-Phe(2,4-DiCH3)-OH
CAS Number
1217728-65-8
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4
Molecular Weight
415.48
MDL Number
MFCD06659141
PubChem ID
11589726
Appearance
White powder
Optical Rotation
[a]D25 = -43 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(2,4-DiCH3)-OH, (S)-Fmoc-2-amino-3-(2,4-dimethylphenyl)propionic acid, Fmoc-Phe(2,4-DiCH3)-OH
CAS Number
1217728-65-8
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4
Molecular Weight
415.48
MDL Number
MFCD06659141
PubChem ID
11589726
Appearance
White powder
Optical Rotation
[a]D25 = -43 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-2,4-dimethylphenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex peptide structures efficiently.
  • Drug Development: Its unique properties allow for the development of novel pharmaceuticals, especially in the field of targeted therapies where specific amino acid modifications can enhance drug efficacy.
  • Biotechnology: Used in the production of bioconjugates, this chemical helps in attaching biomolecules to surfaces or other molecules, which is crucial for creating biosensors and diagnostic tools.
  • Research on Protein Folding: The compound aids in studying protein folding mechanisms, providing insights that are essential for understanding diseases related to misfolded proteins.
  • Material Science: Its incorporation into polymer matrices enhances the properties of materials, making it useful in creating advanced materials with tailored functionalities for various applications.

Citations