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Catalog Number:
39669
CAS Number:
955094-26-5
Éster maleimida-PEG 2 -NHS
Purity:
≥ 98 % (HPLC)
Synonym(s):
Éster maleimida-PEG2-succinimidilo, N -succinimidilo13-maleimido-11-oxo-4,7-dioxa-10-azatridecanoato, Éster N -succinimidílico del ácido 13-maleimido-11-oxo-4,7-dioxa-10-azatridecanoico, 3-[2-[2-[3-(2,5-Dioxo-2,5-dihidro-1 H -pirrol-1-il)propanamido]etoxi]etoxi]propanoato de 2,5-doxopirrolidin-1-ilo
Documents
$165.65 /50 mg
Tamaño
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Información del producto

Maleimide-PEG2-NHS ester is a versatile compound widely utilized in bioconjugation and drug delivery applications. This compound features a maleimide group that allows for specific and efficient conjugation to thiol-containing biomolecules, making it an excellent choice for researchers looking to create stable linkages in protein labeling and modification. The polyethylene glycol (PEG) component enhances solubility and biocompatibility, which is crucial for therapeutic applications, particularly in the development of targeted drug delivery systems.

In addition to its use in bioconjugation, Maleimide-PEG2-NHS ester is also employed in the synthesis of antibody-drug conjugates (ADCs), where it facilitates the attachment of cytotoxic agents to antibodies, thereby improving the selectivity and efficacy of cancer therapies. Its unique properties, such as the ability to form stable amide bonds and its favorable pharmacokinetic profile, make it a preferred choice among professionals in the pharmaceutical and biotechnology sectors. Researchers can leverage this compound to enhance the performance of their biomolecular constructs, leading to innovative solutions in diagnostics and therapeutics.

Número CAS
955094-26-5
Fórmula molecular
C18H23N3O9
Peso molecular
425.39
Número MDL
MFCD11041137
Punto de fusión
90 - 94 °C (Lit.)
Condiciones
Conservar a ≤ -10 °C
Información general
Número CAS
955094-26-5
Fórmula molecular
C18H23N3O9
Peso molecular
425.39
Número MDL
MFCD11041137
Punto de fusión
90 - 94 °C (Lit.)
Condiciones
Conservar a ≤ -10 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Maleimide-PEG2-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its ability to form stable linkages makes it ideal for creating drug delivery vehicles that release therapeutic agents in a controlled manner, improving treatment efficacy.
  • Diagnostic Applications: Utilized in the development of assays and imaging agents, it helps in the detection of diseases by enabling the labeling of specific biomarkers.
  • Polymer Chemistry: This chemical serves as a building block for synthesizing functionalized polymers, which are used in various applications, including tissue engineering and regenerative medicine.
  • Research Tools: It is a valuable reagent in laboratories for creating custom probes and labels, facilitating advanced research in molecular biology and biochemistry.

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