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Catalog Number:
38240
CAS Number:
112887-68-0
Raltitrex
Purity:
≥ 98 % (HPLC)
Synonym(s):
Ácido N -[[5-[[(1,4-Dihidro-2-metil-4-oxo-6-quinazolinil)metil]metilamino]-2-tienil]carbonil]-L-glutámico, ICI-D-1694
Hazmat
Documents
$334.10 /50 mg
Tamaño
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Información del producto

Raltitrexed is a potent antifolate compound primarily utilized in the treatment of various cancers, particularly colorectal cancer. As a thymidylate synthase inhibitor, it disrupts DNA synthesis, making it an essential agent in chemotherapy regimens. Its unique mechanism of action allows for effective targeting of rapidly dividing cancer cells, providing a valuable option for oncologists seeking to enhance patient outcomes. Raltitrexed is often favored for its ability to overcome resistance to other chemotherapeutic agents, making it a critical component in combination therapies.

In addition to its primary applications in oncology, Raltitrexed has shown promise in research settings, particularly in studies focused on cellular metabolism and the development of novel therapeutic strategies. Its specific structure allows for targeted modifications, which can lead to the development of new derivatives with improved efficacy and reduced side effects. Researchers and industry professionals can leverage Raltitrexed's unique properties to explore innovative treatment avenues and enhance existing cancer therapies.

Número CAS
112887-68-0
Fórmula molecular
C21H22N4O6S
Peso molecular
458.49
Número MDL
MFCD00864168
Punto de fusión
176 °C (descenso)
Rotación óptica
[a] D 20 = -15 a -20 ° (C=1 en MeOH)
Condiciones
Conservar a < 0 °C
Información general
Número CAS
112887-68-0
Fórmula molecular
C21H22N4O6S
Peso molecular
458.49
Número MDL
MFCD00864168
Punto de fusión
176 °C (descenso)
Rotación óptica
[a] D 20 = -15 a -20 ° (C=1 en MeOH)
Condiciones
Conservar a < 0 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Raltitrexed is widely utilized in research focused on

  • Cancer Treatment: This compound is primarily used as an anti-cancer agent, particularly in the treatment of colorectal cancer. It acts as a thymidylate synthase inhibitor, disrupting DNA synthesis in rapidly dividing cancer cells.
  • Pharmaceutical Development: Raltitrexed serves as a critical reference compound in the development of new anti-cancer drugs. Researchers study its mechanisms to design more effective therapies with fewer side effects.
  • Combination Therapies: It is often used in combination with other chemotherapeutic agents to enhance treatment efficacy. This synergistic approach can improve patient outcomes in various cancer types.
  • Clinical Trials: Raltitrexed is frequently involved in clinical trials aimed at evaluating new treatment regimens. Its established profile helps researchers assess the effectiveness of novel therapeutic strategies.
  • Research on Drug Resistance: Scientists study Raltitrexed to understand mechanisms of drug resistance in cancer cells. Insights gained can lead to the development of strategies to overcome resistance and improve treatment success.

Citas